Toshinori Okinaga et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 35(6), 431-440 (2015-03-20)
Interleukin-1 (IL-1) cytokines, IL-1α, IL-1β, and IL-18 play a crucial role in inflammatory responses in a variety of diseases including periodontitis. In this study, the periodontopathic bacterial pathogen, Aggregatibacter actinomycetemcomitans, induced cell death and cytokine release in macrophages. Cell viability