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Annett Isabel Walker et al.
International archives of allergy and immunology, 155(1), 86-92 (2010-11-27)
Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the administration of corticosteroids esterified with succinate. Skin tests, basophil activation tests
T Velpandian et al.
Methods and findings in experimental and clinical pharmacology, 32(3), 171-179 (2010-05-08)
The present study evaluated the protective action of calcium dobesilate (CDO) in various experimental models of cataract. CDO was studied in hydrocortisone-induced cataract in developing chick embryos and selenite-induced cataract in pups. CDO anti-cataract activity was also evaluated after oral
Ryoukichi Ikeda et al.
Auris, nasus, larynx, 37(1), 114-116 (2009-05-05)
With the increase in the number of patients undergoing warfarin therapy, reports of complications due to such therapy have become frequent. Although upper airway obstruction secondary to bleeding resulting from warfarin therapy is rare, it is a life-threatening complication because
Lingjie Li et al.
Cell stem cell, 24(2), 271-284 (2019-01-29)
Tissue development results from lineage-specific transcription factors (TFs) programming a dynamic chromatin landscape through progressive cell fate transitions. Here, we define epigenomic landscape during epidermal differentiation of human pluripotent stem cells (PSCs) and create inference networks that integrate gene expression
Sami Karoui et al.
La Tunisie medicale, 86(4), 322-327 (2009-05-30)
To investigate the efficacy of azathioprine as maintenance therapy in acute severe colitis of Crohn's disease or ulcerative colitis after successful treatment by intravenous corticosteroids. We conduct an open prospective study between 1999 and 2004. All patients with acute severe
Robert H Whitehead et al.
American journal of physiology. Gastrointestinal and liver physiology, 296(3), G455-G460 (2008-12-26)
It has proved to be impossible to culture epithelial cells from the gastrointestinal tract of adult animals. Researchers have had to use either cell lines derived from newborn rat small intestine or colon carcinoma cell lines that have retained some
Mark P Yeager et al.
Critical care medicine, 37(10), 2727-2732 (2009-11-04)
There is continuing controversy regarding the effect of glucocorticoids on a systemic inflammatory process. Based ona model of glucocorticoid action that includes both pro- and anti-inflammatory effects, we used the human experimental endotoxemia model to test the hypothesis that a
Noriko Hikita-Watanabe et al.
Acta oto-laryngologica, 130(1), 79-83 (2009-05-14)
The 'tinnitus-rare' group had a poorer prognosis for hearing than the 'tinnitus-often' group in all sudden sensorineural hearing loss (SSNHL), although the 'shorter duration' group had better prognosis than the 'longer duration' when restricted to SSNHL accompanied by tinnitus. This
[Rhabdomyolysis in severe acute asthma].
A Awab et al.
Annales francaises d'anesthesie et de reanimation, 28(2), 171-172 (2009-01-23)
Setsuko Morinaka
Auris, nasus, larynx, 36(5), 606-608 (2009-03-07)
A 73-year-old man presented to our hospital with a sore throat (left-sided) and hiccups. The patient had mucosal swelling and erosions affecting the left posterior pillar, base of tongue, epiglottis, arytenoid, and aryepiglottic fold. As the laryngeal mucosal edema became
Eleonora Nucera et al.
European journal of endocrinology, 164(1), 139-140 (2010-10-22)
We present the case of a woman with 'empty sella syndrome' who experienced generalized urticaria after the administration of sodium succinate hydrocortisone in two episodes. The patient underwent an allergological evaluation (prick, intradermal, and patch tests) with hydrocortisone sodium succinate
Maiko Miyagawa et al.
Acta oto-laryngologica, 129(11), 1326-1329 (2009-10-30)
A 53-year-old male with fluctuating low frequency sensorineural hearing loss and tinnitus, but without vertigo, was evaluated by MRI obtained by intratympanic injection of a gadolinium-based contrast agent (GBCA) before and after the administration of isosorbide. The endolymphatic hydrops was
Thomas Colley et al.
The Journal of antimicrobial chemotherapy, 74(10), 2950-2958 (2019-07-31)
The growing emergence of azole-resistant Aspergillus fumigatus strains worldwide is a major concern for current systemic antifungal treatment. Here we report antifungal activities of a novel inhaled triazole, PC1244, against a collection of multi-azole-resistant A. fumigatus strains. MICs of PC1244
Influence Of Cortisol On The Attachment And Metamorphosis Of Larval Utterbackia Imbecillis On Bluegill Sunfish (Lepomis Macrochirus).
Dubansky, B., et al.
The Biochemical Journal, 220, 97-106 (2011)
Shengxian Liang et al.
Ecotoxicology and environmental safety, 174, 353-362 (2019-03-09)
The liver is one of the major targets of hormones, including thyroid hormones (THs), and many industrial chemicals, such as endocrine-disrupting chemicals. Those compounds may permeate the placenta barrier and pose a risk for embryonic development. Therefore, it is necessary
Yuri Nambu et al.
Neuroscience letters, 748, 135732-135732 (2021-02-17)
The discovery of neural stem cells (NSCs) in the adult mammalian brain has provided insights into an extra level of brain plasticity. The proliferation and differentiation of NSCs is modulated by various physiological, pathological, and pharmacological stimuli. NSCs were recently
Brian H Cuthbertson et al.
Intensive care medicine, 35(11), 1868-1876 (2009-08-05)
Use of etomidate in the critically ill is controversial due to its links with an inadequate response to corticotropin and potential for excess mortality. In a septic shock population, we tested the hypotheses that etomidate administration induces more non-responders to
He Li et al.
Neurological research, 33(3), 295-299 (2011-04-26)
The effects of hydrocortisone sodium succinate on voltage-gated sodium current (I(Na)) were investigated by using the patch-clamp technique in trigeminal ganglion (TG) neurons of rat. I(Na) was recorded by whole-cell patch-clamp techniques after different concentrations of hydrocortisone sodium succinate were
Fang Deng et al.
Clinical rheumatology, 29(4), 369-374 (2009-12-25)
The objective of this study was to identify the most effective treatment by evaluating the different therapies used to treat mild, moderate, and severe Henoch-Schönlein purpura (HSP) patients. We performed a retrospective study of children discharged with a diagnosis of
Kelsey A Hart et al.
American journal of veterinary research, 73(1), 68-75 (2011-12-30)
To compare daily endogenous cortisol production rate and the pharmacokinetics of an i.v. bolus of hydrocortisone between neonatal foals and adult horses. 10 healthy full-term 2- to 4-day-old foals and 7 healthy adult horses. Blood samples were collected from each
Y Baert et al.
Human reproduction (Oxford, England), 35(5), 1029-1044 (2020-05-12)
Is it possible to co-culture and functionally link human liver and testis equivalents in the combined medium circuit of a multi-organ chip? Multi-organ-chip co-cultures of human liver and testis equivalents were maintained at a steady-state for at least 1 week and
Sebastián Tornero Patricio et al.
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 56(1), 40-42 (2009-07-25)
X-linked adrenoleukodystrophy is an inherited metabolic disease caused by the accumulation of saturated very long chain fatty acids (VLCFA). Given that the form of presentation can be primary adrenal insufficiency, diagnosis in affected males is important. Patient was a 4-year-old
Raha Rahbari et al.
Pharmaceutics, 12(12) (2020-12-19)
Polymer-based solid microstructures (MSts) have the potential to significantly increase the quantity and range of drugs that can be administered across the skin. MSt arrays are used to demonstrate their capacity to bypass the skin barrier and enhance permeability by
Susan W Aucott et al.
Pediatrics, 122(4), 775-781 (2008-10-03)
Relative adrenal insufficiency in extremely low birth weight infants may contribute to significant morbidity and death. Our objective was to evaluate the relationship between cortisol concentrations and short-term outcomes. Cortisol concentrations were obtained for 350 intubated, extremely low birth weight
Thomas Colley et al.
Antimicrobial agents and chemotherapy, 62(5) (2018-02-15)
The antifungal effects of the novel triazole PC1244, designed for topical or inhaled administration, against Aspergillus fumigatus were tested in a range of in vitro and in vivo studies. PC1244 demonstrated potent antifungal activities against clinical A. fumigatus isolates (n
Naked & unconscious: crew's misdiagnosis could have cost patient her life.
Kimberly Doran
JEMS : a journal of emergency medical services, 37(10), 28-28 (2013-01-25)
Jian-hua Lin et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 30(2), 377-378 (2010-02-18)
To study the therapeutic effect of glucocorticoid on early postoperative cholangiole cholestasis hyperbilirubinemia after liver transplantation. Thirteen liver transplantation recipients with serum total bilirubin above 171 micromol/L at two weeks to one month postoperatively were enrolled in this study. After
Xiaoxing Liang et al.
Journal of hazardous materials, 407, 124387-124387 (2020-11-12)
The widely used chemical bisphenol A (BPA) has been associated with several health effects. In recent years, many derivatives were developed to replace BPA although without thorough toxicological evaluation. Here, we employed a human embryoid body (EB)-based in vitro global
Wendy Saltzman et al.
Psychoneuroendocrinology, 34(8), 1222-1234 (2009-04-14)
Both acute and chronic stress can impair maternal behavior and increase rates of infant abuse in several species. The mechanisms inducing these effects are unknown, but experimental manipulation of circulating corticosterone levels alters maternal behavior in rats, and circulating or
Crenguta Livia Calma et al.
Tropical doctor, 42(1), 54-55 (2011-11-08)
This case report focuses on hydatidosis, one of the most important parasitic zoonoses in Romania. We describe an interesting paediatric case of an eight-year old boy from a rural region presenting with a both giant and life-threatening pulmonary cyst (that
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