Figure 1. Note: While the above scheme depicts a generic decarboxylative coupling reaction, High-Throughput Photocatalysis Screening Kit can be used for any photocatalytic transformation
Note: This recipe makes 25 mL which is enough stock solution for both screening sets in the KitAlysis™ Photocatalysis Reaction Screening Kit. The amount of internal standard is 10 mol% per reaction, so a big product peak to small internal standard indicates a good reaction. Integrate to compare reactions against one another (product/internal standard).
Figure 2.Sealing the Plate-screwing down the cover
Sealing the plate properly is critical to success. The key is light, even pressure to the lid of the block to keep the cover flat while sealing.
Due to narrow opening of pipette tips, slurry additions will result in blockages. To aid in uniform dosing, simply snip off the end of the tip at the first marker (~10 mm). To ensure an evenly dispersed aliquot, it is critical that the mixture is stirring well while you draw aliquots for dosing into the corresponding reaction vial.
Figure 3.Snip Pipette