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Merck

APOE

apolipoprotein E

Sinónimos:
AD2, LDLCQ5, LPG
Especie:
ID UniProtKB:
ID del gen:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Human APOE / Apolipoprotein E ELISA Kit, ,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-APOE (C-terminal) antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

Proteins

Número de producto
Descripción
Especie
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Especie
human
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Especie
human
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Especie
human
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Especie
human
Lipoprotein, high density from human plasma, lyophilized powder,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Apoe,
Especie
mouse