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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Sinónimos:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Especie:
ID UniProtKB:
ID del gen:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-E-Cadherin antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP64, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CDH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
Reactividad de especies
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Cell Lines

Número de producto
Descripción
Especie
MCF10A CELLS CDH1 (-/-), ,
Especie
human

Proteins

Número de producto
Descripción
Especie
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Especie
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Especie
mouse
E-Cadherin/ECAD/Cadherin-1/CD324 Protein human, recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CDH1,
Especie
human
MISSION® esiRNA, targeting mouse Cdh1,
Especie
mouse