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Merck

DRD4

dopamine receptor D4

Sinónimos:
D4DR
Especie:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)
ID UniProtKB:
P21917, B0M0J7, Q7Z7Q5, Q8NGM5
ID del gen:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

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Small Molecule - Agonist

Número de producto
Descripción
Especie
A1237
Pramipexole dihydrochloride, >98% (HPLC), powder,
Especie
human
R2530
Ropinirole hydrochloride, powder, ≥98% (HPLC),
Especie
human
PHR1633
Ropinirole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1605205
Ropinirole hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Y0001465
Apomorphine hydrochloride hemihydrate, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Número de producto
Descripción
Especie
L131
L-745,870 hydrochloride, ,
Especie
human
L135
L-741,626, ≥98% (HPLC),
Especie
human
46674
Promazine hydrochloride, VETRANAL®, analytical standard,
Especie
human
BP856
Chlorpromazine hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
1229001
Droperidol, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
HPA062682
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
D052
GBR 12909 dihydrochloride, solid, ≥98% (HPLC),
Especie
human
1031401
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
I119
Indatraline hydrochloride, solid,
Especie
human
594687
α-Sexithiophene, ,
Especie
human, rat
51330
Harmaline, ≥95%,
Especie
human, rat

Small Molecule - Metabolite

Número de producto
Descripción
Especie
H3132
3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,
Especie
human

Small Molecule - Precursor

Número de producto
Descripción
Especie
D9628
3,4-Dihidroxi-L-fenilalanina, ≥98% (TLC),
Especie
mouse, human, rat
D9503
3,4-Dihydroxy-DL-phenylalanine, ,
Especie
mouse, human, rat

esiRNA

Número de producto
Descripción
Especie
EMU028911
MISSION® esiRNA, targeting mouse Drd4,
Especie
mouse