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Merck

MAP2K5

mitogen-activated protein kinase kinase 5

Sinónimos:
HsT17454, MAPKK5, MEK5, PRKMK5
Especie:
ID UniProtKB:
ID del gen:
  • Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
  • Mouse(23938) mitogen-activated protein kinase kinase 5
  • Rat(29568) mitogen activated protein kinase kinase 5
  • Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
  • domestic cat(101100725) mitogen-activated protein kinase kinase 5
  • sheep(101104069) mitogen-activated protein kinase kinase 5
  • chicken(415557) mitogen-activated protein kinase kinase 5
  • dog(609559) mitogen-activated protein kinase kinase 5
  • cow(100295732) mitogen-activated protein kinase kinase 5
  • domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5
  • naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
  • Horse(100052849) mitogen-activated protein kinase kinase 5
  • Zebrafish(100007679) mitogen-activated protein kinase kinase 5

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-MEK5 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
PD 98,059, solid,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human MAP2K5,
Especie
human
MISSION® esiRNA, targeting mouse Map2k5,
Especie
mouse