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Merck

MAPK3

mitogen-activated protein kinase 3

Sinónimos:
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Especie:
ID UniProtKB:
ID del gen:
  • Human(5595) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26417) mitogen-activated protein kinase 3
  • Rat(50689) mitogen activated protein kinase 3
  • Zebrafish(399480) mitogen-activated protein kinase 3
  • domestic cat(101087958) mitogen-activated protein kinase 3
  • cow(531391) mitogen-activated protein kinase 3
  • Horse(100066173) mitogen-activated protein kinase 3
  • dog(479790) mitogen-activated protein kinase 3
  • sheep(101123008) mitogen-activated protein kinase 3
  • naked mole-rat(101702687) mitogen-activated protein kinase 3
  • domestic guinea pig(100725692) mitogen-activated protein kinase 3

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Phospho-Erk1 (pThr202 / pTyr204 + Erk2 (pTyr185/187) and pan-Erk1 / 2 ELISA Kit, for detection of phospho-erk1 and phospho-erk2 and pan-erk1/2 in human, mouse or rat cell and tissue lysates,
Especie
human
Phospho-Erk1 (pThr202 / pTyr204) + Erk2(pTyr185/187) ELISA Kit, for detection of phospho-erk1 and phospho-erk2 in human, mouse or rat cell and tissue lysates,
Especie
human
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Especie
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Especie
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Especie
rat, human, mouse

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
KD-Validated Anti ERK1 Antibody, clone 23GB2455, Rabbit Monoclonal, clone 23GB2455, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
KD-Validated Anti ERK1 Antibody, clone 23GB2450, Rabbit Monoclonal, clone 23GB2450, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence

western blot
Anti-phospho-Erk1 (Thr202/Tyr204) + Erk2 (Thr185/Tyr187) Antibody, clone 23GB4520, Rabbit Monoclonal, clone 23GB4520, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence

western blot
Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-MAPK3 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Número de producto
Descripción
Especie
ERK1, active, untagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
ERK1, active, GST tagged human, PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Mapk3,
Especie
mouse
MISSION® esiRNA, targeting human MAPK3,
Especie
human