MMP14
matrix metallopeptidase 14 (membrane-inserted)
Sinónimos:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
Especie:
Human MMP14 (4323), Mouse Mmp14 (17387), Rat Mmp14 (81707), naked mole-rat Mmp14 (101723795), sheep MMP14 (443116), cow MMP14 (281915), Domestic Rabbit MMP14 (100009598), domestic guinea pig Mmp14 (100732039), dog MMP14 (403823), Horse MMP14 (100034170) ...Más
ID UniProtKB:
ID del gen:
- Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
- Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
- Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
- naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
- sheep(443116) matrix metallopeptidase 14 (membrane-inserted)
- cow(281915) matrix metallopeptidase 14 (membrane-inserted)
- Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
- domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
- dog(403823) matrix metallopeptidase 14 (membrane-inserted)
- Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
- domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
- chicken(426253) matrix metallopeptidase 14 (membrane-inserted)
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-MMP14 (Cleaved-Tyr112) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MMP14/MT1-MMP antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot