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Merck

NOS1

nitric oxide synthase 1 (neuronal)

Sinónimos:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
Especie:
ID UniProtKB:
ID del gen:
  • Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(18125) nitric oxide synthase 1, neuronal
  • Rat(24598) nitric oxide synthase 1, neuronal
  • Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
  • naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
  • cow(536132) nitric oxide synthase 1 (neuronal)
  • domestic cat(101100342) nitric oxide synthase 1 (neuronal)
  • Zebrafish(60658) nitric oxide synthase 1 (neuronal)
  • Horse(100051079) nitric oxide synthase 1 (neuronal)
  • dog(477498) nitric oxide synthase 1 (neuronal)
  • chicken(427721) nitric oxide synthase 1 (neuronal)
  • domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número de producto
Descripción
Especie
(−)-Thalidomide, >98%, solid,
Especie
human, mouse, rat
(+)-Thalidomide, ≥98% (HPLC), powder,
Especie
human, mouse, rat
Ammonium pyrrolidinedithiocarbamate, ~99%,
Especie
human
Melatonina, powder, ≥98% (TLC),
Especie
human
(±)-Thalidomide, ≥98%, powder,
Especie
human, mouse, rat

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Nitrotyrosine antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
wide range
Aplicación
ELISA
immunofluorescence

immunohistochemistry

microarray

western blot
Anti-NOS1 (Ab-852) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
Monoclonal Anti-Nitrotyrosine antibody produced in mouse, clone 39B6, 1 mg/mL, purified immunoglobulin,
Reactividad de especies
dog, human, mouse, rat
Aplicación
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-NOS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-NOS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Spermidine trihydrochloride, ≥98% (TLC),
Especie
human
4-Nitrocatechol, ≥96.0%,
Especie
rat
5-Methyl-2-nitroaniline, 95%,
Especie
rat
L-arginina, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Especie
rat, human
L-arginina, reagent grade, ≥98%,
Especie
rat, human

Kits

Número de producto
Descripción
Especie
Nitric Oxide Synthase Detection System, Fluorimetric, sufficient for 200 reactions,
Especie
human

Small Molecule - Precursor

Número de producto
Descripción
Especie
L-arginina, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Especie
rat, human
L-arginina, reagent grade, ≥98%,
Especie
rat, human
L-arginina, BioUltra, ≥99.5% (NT),
Especie
rat, human
L-arginina, 99%, FCC, FG,
Especie
rat, human
L-arginina, ,
Especie
rat, human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Nos1,
Especie
mouse