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Merck

TMPRSS2

transmembrane protease, serine 2

Sinónimos:
PP9284, PRSS10
Especie:
ID UniProtKB:
ID del gen:
  • Human(7113) Summary: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(50528) transmembrane protease, serine 2
  • Rat(156435) transmembrane protease, serine 2
  • cow(511037) transmembrane protease, serine 2
  • sheep(101120216) transmembrane protease, serine 2
  • Zebrafish(494080) transmembrane protease, serine 2
  • chicken(418528) transmembrane protease, serine 2
  • domestic cat(101096004) transmembrane protease, serine 2
  • naked mole-rat(101715175) transmembrane protease, serine 2
  • domestic guinea pig(100732077) transmembrane protease, serine 2
  • dog(487770) transmembrane protease, serine 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TMPRSS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TMPRSS2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12511, purified by using Protein A, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-TMPRSS2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12512, purified by using Protein A, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-TMPRSS2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-TMPRSS2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12514, purified by using Protein A, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human TMPRSS2,
Especie
human