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281778

(3-Aminopropyl)trimethoxysilane

97%

Sinónimos:

3-(Trimethoxysilyl)propylamine

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A ustedes/SKUDisponibilidadPrecio
5 mL
Comprobar disponibilidad del carrito
MXP 1,607.00
100 mL
Comprobar disponibilidad del carrito
MXP 2,495.00
500 mL
Comprobar disponibilidad del carrito
MXP 7,149.00

Acerca de este artículo

Fórmula lineal:
H2N(CH2)3Si(OCH3)3
Número CAS:
Peso molecular:
179.29
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
237-511-5
Beilstein/REAXYS Number:
2038118
MDL number:

MXP 1,607.00


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Quality Segment

assay

97%

form

liquid

refractive index

n20/D 1.424 (lit.)

bp

91-92 °C/15 mmHg (lit.)

density

1.027 g/mL at 25 °C (lit.)

SMILES string

CO[Si](CCCN)(OC)OC

InChI

1S/C6H17NO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-7H2,1-3H3

InChI key

SJECZPVISLOESU-UHFFFAOYSA-N

General description

(3-Aminopropyl)trimethoxysilane (APTMS) is a high-reactivity aminosilane engineered for the deposition of cationic Self-Assembled Monolayers (SAMs) on inorganic substrates. Its trimethoxy structure ensures faster hydrolysis and denser surface grafting compared to ethoxy-silanes, providing a terminal primary amine (-NH2) handle for the covalent attachment of biomolecules, polymers, and fluorophores. Beyond biotechnology, APTMS is a pivotal interfacial modifier in nanoelectronics, where it passivates dielectric surfaces to enhance charge-carrier mobility in organic field-effect transistors (OFETs) and enables the precise alignment of carbon nanotubes and graphene. Refined to a 97% high-purity specification, this grade is engineered to provide excellent consistency for applications requiring precise and reliable surface functionalization.

Application

As a versatile molecular bridge, APTMS is essential for engineering intelligent interfaces and stimuli-responsive systems that enable precise interactions at the intersection of nanotechnology, biology, and electronics.

Stimuli-Responsive Nanocarriers: Functionalizes mesoporous silica pores to create pH-sensitive "gatekeepers" that trigger drug release specifically within acidic tumor microenvironments.

Gene & Nucleic Acid Delivery: Modulates the surface zeta potential of nanoparticles to facilitate high-efficiency electrostatic loading and endosomal escape of siRNA, mRNA, and pDNA.

Precision Bioconjugation: Acts as a molecular bridge for anchoring targeting ligands (e.g., Folate, RGD peptides) or PEG chains to gold and iron oxide nanoparticles for enhanced circulation and cell-specific uptake.

Advanced Biosensing: Utilized in LSPR-based diagnostics to immobilize antibodies onto gold nanostructures, enabling real-time detection of clinical biomarkers such as C-reactive protein (CRP).

Neuro-Targeting: Recent findings highlight its role in tuning nanoparticle surface charge to improve Blood-Brain Barrier (BBB) permeability via adsorptive-mediated transcytosis

Packaging

Optically tunable core-shell composite nanorod structures have been prepared by depositing gold onto silica and titania nanorods which have been surface modified with (3-Aminopropyl)trimethoxysilane

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Este artículo
175617741442440140
refractive index

n20/D 1.424 (lit.)

refractive index

n20/D 1.444 (lit.)

refractive index

n20/D 1.421

refractive index

-

density

1.027 g/mL at 25 °C (lit.)

density

1.057 g/mL at 25 °C (lit.)

density

0.929 g/mL at 25 °C, 0.946 g/mL at 25 °C (lit.)

density

0.946 g/mL at 25 °C (lit.)

bp

91-92 °C/15 mmHg (lit.)

bp

213-215 °C (lit.)

bp

217 °C/760 mmHg (lit.)

bp

217 °C/760 mmHg (lit.)

assay

97%

assay

95%

assay

≥98.0%

assay

99%

form

liquid

form

liquid

form

liquid

form

liquid

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Clase de almacenamiento

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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