335452

Lithium (trimethylsilyl)acetylide solution

0.5 M in THF

• Synonym(s): (Trimethylsilyl)ethynyllithium
• Linear Formula: (CH₃)₃SiC≡CLi
• CAS Number: 54655-07-1
• Molecular Weight: 104.15
• Beilstein: 3587411
• Número MDL: MFCD00075059
• ID de la sustancia en PubChem: 24860321
• NACRES: NA.22

Properties

• formulario: liquid
• Nivel de calidad: 100
• concentración: 0.5 M in THF
• densidad: 0.88 g/mL at 25 °C
• SMILES string: [Li]C#C[Si](C)(C)C
• InChI: 1S/C5H9Si.Li/c1-5-6(2,3)4;/h2-4H3;
• InChI key: ZVXXEONXFWSCIZ-UHFFFAOYSA-N

Description

Aplicación

Lithium (trimethylsilyl)acetylide can be used as a reagent:

• In the transmetalation and nucleophilic displacement reactions.
• To prepare propargylic alcohol derivatives by reacting with aldehydes and ketones.
• To synthesize α,βynones by treating with Weinreb amide or with isoxazolidide.
• Along with Grignard reagent to convert γ- and δ-thiolactams to thioiminium salts, which are employed as key intermediates to produce disubstituted pyrrolidines.

Reacts with halotriazines to produce conductive, anisotropic carbon-nitrogen materials.

Envase

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Información legal

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictogramas: GHS02,GHS05,GHS07,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225 - H302 - H314 - H335 - H336 - H351
• Consejos de prudencia: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Riesgos supl.: EUH019
• Código de clase de almacenamiento: 3 - Flammable liquids
• WGK: WGK 3
• Punto de inflamabilidad F: -9.4 °F - closed cup
• Punto de inflamabilidad C: -23 °C - closed cup
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter