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Boxed reaction: Sonogashira Reaction in Lipshutz Surfactant

greener alternative

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst

Nivel de calidad


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categoría alternativa más sostenible

temp. de almacenamiento


Descripción general

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here.


This kit contains the reagents, catalyst, and solvent required to perform a Sonogashira reaction in TPGS-750-M, a surfactant developed by the Lipshutz group as a greener alternative to organic solvents. This technology allows common metal-catalyzed reactions to be run under aqueous conditions, considerably reducing solvent waste. The components are pre-weighed in the appropriate amounts for a 1 mmol scale reaction.

Please refer to the attached Protocol for details.

Kit Components Also Available Separately

Product No.

  • 225657Bis(acetonitrile)dichloropalladium(II), 99% 5 mg

  • 638064XPhos, 98% 12 mg

  • 763918DL-α-Tocopherol methoxypolyethylene glycol succinate solution, 5 wt. % in H2O 2 mL

  • T0886Triethylamine, ≥99% .28 mL

Palabra de señalización


Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 4 - Flam. Liq. 2 - Skin Corr. 1A

Código de clase de almacenamiento

3 - Flammable liquids

Punto de inflamabilidad F

5.0 °F

Punto de inflamabilidad C

-15 °C

Certificate of Analysis

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Certificate of Origin

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