Todas las fotos(1)

779873

Sigma-Aldrich

Methyl-β-cyclodextrin

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% cyclodextrin basis

Sinónimos:
Cavasol W7 M Life Science, MβCD, Methyl-beta-cyclodextrin
Número de CAS:
NACRES:
NA.22

Nivel de calidad

200

grado

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

ensayo

≥98.0% cyclodextrin basis

actividad óptica

[α]/D 154.0 to 156.0°

mol peso

Mw 1310 g/mol

extensión del etiquetado

1.7-1.9 molar substitution

impurezas

≤0.10% unsubstituted cyclodextrin
≤0.20% chloride
≤0.50% reducing substances
≤50 ppm volatile organics

residuo de ign.

≤0.50%

pérdida

≤5.0% loss on drying

mp

180-182 °C (lit.)

absorción

≤0.10 at 350-600 nm in solution at 10%
≤1.00 at 220-350 nm in solution at 10%

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

¿Está buscando productos similares? Visit Guía de comparación de productos

Aplicación

Methyl-β-cyclodextrin is a macrocyclic compound that can form inclusion complexes with a number of guest molecules. It shows higher solubility in aqueous solutions and greater solubilizing and complexing power compared to the parent β-cyclodextrin. MβCD can be used to enhance the enzyme activity and enantioselectivity of subtilisin enzyme in organic solvents.

Otras notas

For R&D Use

Información legal

Cavasol is a registered trademark of Wacker Chemie AG

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

368.6 °F

Punto de inflamabilidad C

187 °C

Certificado de Análisis

Certificado de origen

Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.
Ribeiro A
Aaps Pharmscitech, 9(4), 1102-1109 (2008)
Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.
Griebenow K
Journal of the American Chemical Society, 121(36), 8157-8163 (1999)
Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
Laurie Hamtiaux et al.
PloS one, 6(10), e26823-e26823 (2011-11-03)
The antitumoral properties of endocannabinoids received a particular attention these last few years. Indeed, these endogenous molecules have been reported to exert cytostatic, apoptotic and antiangiogenic effects in different tumor cell lines and tumor xenografts. Therefore, we investigated the cytotoxicity

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico