Merck
All Photos(2)

C80105

Sigma-Aldrich

Chrysin

97%

Synonym(s):
5,7-Dihydroxyflavone
Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
Molecular Weight:
254.24
Beilstein:
233276
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

97%

form

powder

mp

284-286 °C (lit.)

solubility

0.1 M NaOH: 0.008 g/L

λmax

348 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccccc3

InChI

1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H

InChI key

RTIXKCRFFJGDFG-UHFFFAOYSA-N

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This Item
20190195082PHL80382
Chrysin 97%

Sigma-Aldrich

C80105

Chrysin

Chrysophenine Dye content 65 %

Sigma-Aldrich

201901

Chrysophenine

Chrysin analytical standard

Supelco

95082

Chrysin

Chrysin phyproof® Reference Substance

PHL80382

Chrysin

assay

97%

assay

-

assay

≥98% (HPLC)

assay

≥98.0% (HPLC)

form

powder

form

powder

form

-

form

-

mp

284-286 °C (lit.)

mp

-

mp

284-286 °C (lit.)

mp

284-286 °C (lit.)

solubility

0.1 M NaOH: 0.008 g/L

solubility

-

solubility

-

solubility

-

λmax

348 nm

λmax

389 nm

λmax

-

λmax

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

food and beverages

application(s)

food and beverages

Application

  • Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli.
  • It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line.
  • It has been used to study the effect of chrysin on human ovarian cancer cells.

Biochem/physiol Actions

Chrysin is a flavonoid and an analog of apigenin. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. Chrysin exhibits anti-inflammatory and anti-oxidant effects. This molecule induces apoptosis in various cells, thereby exhibiting cancer chemopreventive activity. Chrysin can modulate the activity of GABAA (Type-A γ-aminobutyric acid) and GABAC receptors, it downregulates expression of PCNA (proliferating cell nuclear antigen), reduces activity of CDK2 (cyclin-dependent kinase 2) and CDK4 and induces p38-MAPK (mitogen-activated protein kinase) activation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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