700029P

3β,7β-dihydroxy-5-cholestenoic acid

Avanti Research^™ - A Croda Brand

• Sinónimos: (25R)-cholest-5-en-26-oic acid, 3β,7β-hydroxy
• Fórmula empírica (notación de Hill): C₂₇H₄₄O₄
• Número de CAS: 1246298-66-7
• Peso molecular: 432.64
• Número MDL: MFCD22416723
• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: powder
• envase: pkg of 1 × 1 mg (700029P-1mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) is associated with plasma and is a C27 acid.[1] 3β,7β-diHCA is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) by the action of the enzyme hydroxysteroid 11-β dehydrogenase 1.[2]

Aplicación

3β,7β-dihydroxy-5-cholestenoic acid may be used as an authentic diastereoisomer standard in mass spectrometry (MS) experiments.[3]

Acciones bioquímicas o fisiológicas

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) levels are elevated in Niemann-Pick type C (NPC) disease and Niemann-Pick (NP) disease type B disorders.[1] It elicits toxicity to oculomotor neurons.[2]

Envase

5 mL Amber Glass Screw Cap Vial (700029P-1mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids