Merck
  • 700056P
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700056P

Avanti

lathosterol-d7

Avanti Polar Lipids 700056P, powder

Synonym(s):
5α-Cholest-7-en-3β-ol (25,26,26,26,27,27,27-d7)
Empirical Formula (Hill Notation):
C27H39D7O
CAS Number:
Molecular Weight:
393.70
NACRES:
NA.25

ensayo

>99% (TLC)

formulario

powder

envase

pkg of 1 × 1 mg (700056P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700056P

enviado en

dry ice

temp. de almacenamiento

−20°C

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assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 1 mg (700056P-1mg)

packaging

pkg of 1 × 10 mg (700069P-10mg), pkg of 1 × 5 mg (700069P-5mg)

packaging

pkg of 1 × 1 mg (700090P-1mg)

packaging

pkg of 1 × 1 mg (700148P-1mg)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Avanti Polar Lipids 700056P

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 700090P

manufacturer/tradename

Avanti Polar Lipids 700148P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Descripción general

Lathosterol is a metabolite of cholesterol present in human breast milk. Lathosterol is catabolized by lathosterol 5-desaturase to 7-dehydrocholesterol, which is a precursor of cholesterol. Lathosterol-d7 is a deuterated derivative of lathosterol.

Aplicación

Lathosterol-d7 has been used as an internal standard in gas chromatography-mass spectrometry (GC–MS) for the breast milk sterol quantification and in liquid chromatography high resolution mass spectrometry (LC–HRMS) analysis.

Acciones bioquímicas o fisiológicas

Lathosterol levels are direct indicators of cholesterol levels and aid in decoding metabolism defects. Elevated levels of lathosterol is implicated in cerebrotendinous xanthomatosis (CTX) and lathosterolosis. The inactivation of enzyme lathosterol 5-desaturase (SC5D) leads to accumulation of lathosterol in lathosterolosis pathology.

Envase

5 mL Amber Glass Screw Cap Vial (700056P-1mg)

Código de clase de almacenamiento

13 - Non Combustible Solids

Punto de inflamabilidad F

No data available

Punto de inflamabilidad C

No data available

Certificate of Analysis

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Certificate of Origin

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