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700066P

Avanti

7-dehydrocholesterol

Δ,5,7-cholesterol, powder

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Sinónimos:
7-dehydrocholesterin; Provitamin D3; 110807
Empirical Formula (Hill Notation):
C27H44O
Número de CAS:
Peso molecular:
384.64
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

powder

envase

pkg of 1 × 5 mg (700066P-5mg)

manufacturer/tradename

Avanti Polar Lipids 700066P

enviado en

dry ice

temp. de almacenamiento

−70°C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3

InChI key

UCTLRSWJYQTBFZ-UHFFFAOYSA-N

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Este artículo
700076P700022P700075P
7-dehydrocholesterol Δ,5,7-cholesterol, powder

Avanti

700066P

7-dehydrocholesterol

8(14)-dehydrocholesterol Avanti Polar Lipids

Avanti

700076P

8(14)-dehydrocholesterol

8(9)-dehydrocholesterol Avanti Polar Lipids

Avanti

700075P

8(9)-dehydrocholesterol

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 5 mg (700066P-5mg)

packaging

pkg of 1 × 1 mg (700076P-1mg)

packaging

pkg of 1 × 1 mg (700022P-1mg)

packaging

pkg of 1 × 1 mg (700075P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700066P

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C

Descripción general

7-dehydrocholesterol is a metabolite produced in cholesterol synthesis. It is an unsaturated sterol predominantly found in the epidermis.

Aplicación

7-dehydrocholesterol has been used:
  • in gas chromatography/mass spectrometry (GC/MS)-based sterol profiling to quantify 7-dehydrocholesterol in oligodendrocyte progenitor cells (OPCs)
  • as an internal standard for the analysis of sterols and oxysterols using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • as an internal standard for lipid measurements by liquid chromatography (LC)-MS

Acciones bioquímicas o fisiológicas

7-dehydrocholesterol acts as a precursor of vitamin D3 under the conditions of high temperature and ultraviolet (UV) light.

Envase

5 mL Amber Glass Screw Cap Vial (700066P-5mg)

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable


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Ejemplo

T1503
Referencia del producto
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25G
Tamaño del envase/cantidad

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Ergosterol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1512

Ergosterol

Lanosterol ≥93%, powder

Sigma-Aldrich

L5768

Lanosterol

Cholecalciferol ≥98% (HPLC)

Sigma-Aldrich

C9756

Cholecalciferol

Cholesterol Sigma Grade, ≥99%

Sigma-Aldrich

C8667

Cholesterol

Biosynthesis of Vitamin D in Skin
Principles of Medical Biology (1997)
Galya Staneva et al.
Langmuir : the ACS journal of surfaces and colloids, 32(6), 1591-1600 (2016-01-20)
7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with 7-dehydrocholesterol interferes with normal cell-signaling processes, which involve interaction between
Devanand K Shenoy et al.
Nano letters, 5(6), 1181-1185 (2005-06-10)
We demonstrate that polymerizable planar membranes permit reconstitution of protein ion channels formed by the bacterial toxins Staphylococcus aureus alpha-hemolysin (alphaHL) and Bacillus anthracis protective antigen 63. The alphaHL channel remained functional even after membrane polymerization. Surface pressure measurements suggest
Manish Sethi et al.
Nanoscale, 6(4), 2321-2327 (2014-01-15)
The effects of nanoparticle (NP) properties, such as size, shape and surface charge, on their efficacy and toxicity have been studied extensively. However, the effect of controlled drug release on NP efficacy and toxicity has not been thoroughly evaluated in
Peng He et al.
Biomacromolecules, 6(5), 2455-2457 (2005-09-13)
These studies show that single-walled carbon nanotubes (SWNTs) can be effectively modified using phospholipids. Using a simple surface modification of SWNTs, followed by deposition of 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine (DCPE) phosphipid, results in stable water-dispersible SWNTs with highly uniform thickness.

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