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700121P

Avanti

sitostanol

β-sitostanol, powder

Sinónimos:

stigmastanol; dihydrositosterol; (3β)-stigmastan-3-ol; (3β,5α)-stigmastan-3-ol

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5 MG
MXP 4,397.00

MXP 4,397.00


Fecha estimada de envío04 de abril de 2025


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5 MG
MXP 4,397.00

About This Item

Fórmula empírica (notación de Hill):
C29H52O
Número de CAS:
Peso molecular:
416.72
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

MXP 4,397.00


Fecha estimada de envío04 de abril de 2025


Solicitar un pedido a granel

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (700121P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 700121P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@H]1C[C@H]2[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CC[C@H](C(C)C)CC)C)(CC3)C)CC2)(CC1)C

InChI

1S/C29H52O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h19-27,30H,7-18H2,1-6H3/t20-,21-,22+,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key

LGJMUZUPVCAVPU-HRJGVYIJSA-N

General description

It is predominantly present in pine oil.[1]
Sitostanol is a 5α-saturated sitosterol derivative.[2]
Sitostanol is a plant stanol[3] and a hydrogenated form of sitosterol.[4]

Application

Sitostanol is suitable for its use as a component in micelle preparation, used for cell culture and cellular uptake studies.[5] It is also suitable for use in cell culture to study its effect on a T-helper-1 shift in peripheral blood mononuclear cells (PBMCs) from asthma patients.[6]
Sitostanol may be used in the preparation of binary phospholipid for thermodynamic studies[7] and Brewster angle microscopy studies.[8] It may also be used as a standard steroid in gas chromatography-mass spectrometry(GC-MS).[9]

Biochem/physiol Actions

Plant stanols are structurally similar to cholesterol, hence it reduces the plasma level of LDL cholesterol.[10] Sitostanol is known to possess hypolipidemic and antiatherogenic effects.[1]
Sitostanol decreases cholesterol absorption.[11] Its ratio with cholesterol is implicated in non-alcoholic fatty liver disease (NAFLD). The ratio also correlates with liver steatosis and inflammation.[3] Sitostanol induces interferon γ production and T-helper response in peripheral blood mononuclear cells (PBMC) in asthma patients.[6] It is a hypocholestremic agent as it decreases the micellar solubility and absorption of cholesterol.[4]
Sitostanol lowers the intestinal absorption of cholesterol and serum cholesterol.[2]

Packaging

5 mL Amber Glass Screw Cap Vial (700121P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids


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Los clientes también vieron

Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population
Miettinen TA, et al.
The New England Journal of Medicine, 333(20), 1308-1312 (1995)
2013 IEEE International Conference on Solid Dielectrics (ICSD) IEEE, 131-131 (2006)
The essential role of cholesterol metabolism in the intracellular survival of Mycobacterium leprae is not coupled to central carbon metabolism and energy production
Marques MAM, et al.
Journal of Bacteriology, 197(23), 3698-3707 (2015)
Corn fiber oil and sitostanol decrease cholesterol absorption independently of intestinal sterol transporters in hamsters
Jain D, et al.
The Journal of Nutritional Biochemistry, 19(4), 229-236 (2008)
Lipids, 217-217 (1999)

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