791637C

15:0-18:1-d7-PC

Avanti Research^™ - A Croda Brand

• Sinónimos: 1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine
• Fórmula empírica (notación de Hill): C₄₁H₇₃ D₇ NO₈ P
• Número CAS: 2097561-16-3
• Peso molecular: 753.09
• MDL number: MFCD22570234
• NACRES: NA.25
• UNSPSC Code: 41141825
• Assay: >99% (TLC)
• Form: liquid

Propiedades

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (791637C-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 1 mg/mL (791637C-1mg)
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) is a deuterated phospholipid. The lipid comprises phosphatidylcholine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phospholipids, in general are amphiphilic and have phosphocholine moiety attached to sn-3 position of glycerol.[1] Phosphatidylcholine is a glycerophospholipid and is a cell membrane component.[2]

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) has been used:

• as a component of extraction solvent for lipid isolation from biological samples [3]
• as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)[4]
• as an internal standard in analysis of lipids from cystic fibrosis derived cell lines[5]

Biochem/physiol Actions

Phosphatidylcholine (PC) levels are crucial for mediating various cellular processes including membrane movement and cell differentiation.[2] A disturbance in PC levels is implicated in various metabolic disorders.[6]

Packaging

2 mL Amber Glass Sealed Ampule (791637C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash