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791638C

Avanti

15:0-18:1-d7-PE

Avanti Polar Lipids

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Sinónimos:
1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine
Fórmula empírica (notación de Hill):
C38H67D7NO8P
Número de CAS:
Peso molecular:
711.01
Código UNSPSC:
41141825
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

liquid

envase

pkg of 1 × 1 mL (791638C-1mg)

fabricante / nombre comercial

Avanti Polar Lipids

concentración

1 mg/mL (791638C-1mg)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Categorías relacionadas

Descripción general

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The lipid comprises phosphatidylethanolamine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylethanolamine is a membrane phospholipid and serves as an intermediate in other glycerophospholipid synthesis.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH® LIPIDOMIX® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Aplicación

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples,
  • as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
  • as an internal standard to spike plasma samples for fourier transform mass spectrometry (FTMS) analysis

Acciones bioquímicas o fisiológicas

Phosphatidylethanolamine (PE) regulates protein folding, protein modification, autophagy and cell division. PE serves as a substrate for glycosylphosphatidylinositol anchored proteins (GPI-APs) synthesis. Low levels of PE may be observed in Parkinson′s disease and may also inhibit protein maturation.

Envase

2 mL Amber Glass Sealed Ampule (791638C-1mg)

Información legal

LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Biomolecules, 9(1) (2018-12-29)
Total fatty acid analysis is a routine method in many areas, including lipotyping of individuals in personalized medicine, analysis of foodstuffs, and optimization of oil production in biotechnology. This analysis is commonly done by converting fatty acyl (FA) chains of
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Bjoern Titz et al.
Computational and structural biotechnology journal, 18, 1056-1073 (2020-05-19)
Cigarette smoke (CS) causes adverse health effects and, for smoker who do not quit, modified risk tobacco products (MRTPs) can be an alternative to reduce the risk of developing smoking-related diseases. Standard toxicological endpoints can lack sensitivity, with systems toxicology
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial

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