V-019

Vitamina B₁₂

Name: Vitamina B<SUB>12</SUB>
Brand: CERILLIAN
Price: 1864 MXP

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

Sinónimos:

α-(5,6-Dimetilbencimidazolil)cianocobamida, CN-Cbl, Cianocob(III)alamina, Cianocobalamina

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1 ML

MXP 1,864.00

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Fórmula empírica (notación de Hill):

C₆₃H₈₈CoN₁₄O₁₄P

Número CAS:

68-19-9

Peso molecular:

1355.37

Beilstein/REAXYS Number:

4122889

EC Number:

200-659-6

UNSPSC Code:

41116107

PubChem Substance ID:

329828962

NACRES:

NA.24

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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@

InChI

1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1

InChI key

RMRCNWBMXRMIRW-QJRSUKKJSA-L

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Este artículo	47869	PHR1234	C3000000
Supelco V-019 Vitamina B₁₂	Supelco 47869 Cianocobalamina (B12)	Supelco PHR1234 Vitamina B₁₂	C3000000 Vitamina B₁₂
application(s) clinical testing clinical testing	application(s) pharmaceutical (small molecule) vitamins, nutraceuticals, and natural products	application(s) pharmaceutical (small molecule) vitamins, nutraceuticals, and natural products	application(s) pharmaceutical (small molecule)
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
form liquid	form -	form -	form solid
Quality Level 300	Quality Level 100	Quality Level 300	Quality Level -
grade certified reference material	grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard
storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

General description

Cyanocobalamin is the most common and widely-produced of the vitamin B12 analogs. Vitamin B12, important for proper neuronal function and formation of blood cellular components, is monitored directly in patient serum samples by LC-MS/MS.

Application

This certified solution standard is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of vitamin B12 deficiency by LC-MS/MS to quality control testing of vitamin B12-based dietary supplements/fortified foods or pharmaceutical preparations.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Referencia del producto

Descripción

Precios

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Tiamina hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

V-015

(−)-Riboflavina, 100 μg/mL (Methanol:0.1% Ammonium acetate in Water (1:1)), ampule of 1 mL, analytical standard, Cerilliant^®

V-016

Nicotinamide, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

V-017

Nicotinic acid, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

V-052

Thiamine-¹³C₃ (Vitamin B₁-¹³C₃) hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant^®

V-055

(-)-Riboflavin-¹³C₄,¹⁵N₂ (Vitamin B2-¹³C₄,¹⁵N₂) solution, 100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant^®

V-067

(−)-Riboflavin, 100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant^®

V-063

Pantothenic acid-¹³C₃,¹⁵N hemicalcium salt solution, 100 μg/mL (90:10 Methanol:Water, (as free acid)), certified reference material, ampule of 1 mL, Cerilliant^®

V-056

Riboflavin 5′-phosphate sodium salt solution, 100 μg/mL (50:50 Methanol:1% Ammonium Acetate in Water, (as free phosphate)), certified reference material, ampule of 1 mL

V-069

Pyridoxal 5′-phosphate solution, 500 μg/mL (80:20 Water:Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant^®

V-080

Pyridoxine-¹³C₃ (Vitamin B6-13C3) hydrochloride solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

F-087

Folic acid solution, 1 mg/mL in methanol with 0.1N NaOH, certified reference material, ampule of 1 mL, Cerilliant^®

F-088

Folic acid-¹³C₅,¹⁵N solution, 100 μg/mL (Methanol with 0.1 N NaOH), certified reference material, ampule of 1 mL, Cerilliant^®

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Clase de almacenamiento

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients: a single blind control trial.

Hossein Khedmat et al.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 24(4), 759-763 (2013-07-03)

Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population. The present

Spinal injection therapy for low back pain.

J Bart Staal et al.

JAMA, 309(23), 2439-2440 (2013-05-18)

Reversible disconnection syndrome: an unusual presentation of vitamin B12 deficiency.

Rajesh Verma et al.

Neurology India, 61(2), 167-169 (2013-05-07)

Vitamin B12 deficiency.

John Paul Killen et al.

The New England journal of medicine, 368(21), 2040-2041 (2013-05-24)

A patient with an inborn error of vitamin B12 metabolism (cblF) detected by newborn screening.

Christine M Armour et al.

Pediatrics, 132(1), e257-e261 (2013-06-19)

A neonate, who was found to have an elevated C3/C2 ratio and minimally elevated propionylcarnitine on newborn screening, was subsequently identified as having the rare cblF inborn error of vitamin B12 (cobalamin) metabolism. This disorder is characterized by the retention

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Protocolos

HPLC Analysis of Vitamins B1 B6 B12

HPLC Analysis of Vitamins B1, B6 and B12 using Ascentis® Express RP-Amide

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Vitamina B12

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®