1.06018

Methanol

for liquid chromatography LiChrosolv^®

• Synonym(s): MeOH, Hydroxymethane, Carbinol, Methyl alcohol
• Linear Formula: CH₃OH
• CAS Number: 67-56-1
• Molecular Weight: 32.04
• Beilstein: 1098229
• Número MDL: MFCD00004595
• Número índice de la CE: 200-659-6

Properties

• grado: HPLC grade; isocratic
• Nivel de calidad: 100
• densidad de vapor: 1.11 (vs air)
• presión de vapor: 128 hPa ( 20 °C); 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)
• Línea del producto: LiChrosolv^®
• ensayo: ≥99.8% (GC)
• formulario: liquid
• temp. de autoignición: 725 °F
• potencia: 5628 mg/kg LD₅₀, oral (Rat); 17100 mg/kg LD₅₀, skin (Rabbit)
• lim. expl.: 36 %
• technique(s): HPLC: suitable
• impurezas: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.03% Water
• residuo de evap.: ≤3.0 mg/L
• color: APHA: ≤10
• transmitancia: 225 nm, ≥50%; 240 nm, ≥80%; 265 nm, ≥98%
• índice de refracción: n20/D 1.329 (lit.)
• kinematic viscosity: 0.54-0.59 cSt(20 °C)
• bp: 64.7 °C (lit.)
• mp: −98 °C (lit.)
• temperatura de transición: flash point 9.7 °C
• densidad: 0.791 g/mL at 25 °C (lit.)
• formato: neat
• temp. de almacenamiento: 2-30°C
• SMILES string: CO
• InChI: 1S/CH4O/c1-2/h2H,1H3
• InChI key: OKKJLVBELUTLKV-UHFFFAOYSA-N

Description

Descripción general

LiChrosolv^® solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Aplicación

Intended for HPLC and UHPLC-MS applications.
Featured in method development of:

• Benazepril - USP Method Benazepril RS
• Betamethasone - USP Method Betamethasone Valerate Assay
• Irbesartan - USP Method Irbesartan Assay
• Lamivudine - USP Method Lamivudine RS
• Lansoprazole - USP Method Lansoprazole RS
• Levofloxacin - USP Method Levofloxacin RS - USP Method Levofloxacin Assay
• Nifedipine - USP Method Nifedipine RS - USP Method Nifedipine Assay
• Pharmacopoeia Monograph Methods - HPLC and UHPLC methods for Regulated Drug Analysis
• Pioglitazone - USP Method Pioglitazone HCl RS - USP Method Pioglitazone HCl Assay

Envase

5 l in Aluminium Bottle

10 , 185 , 30 l in Barrel stainl. st.

2.5 , 4 , 1, 1 l

Características y beneficios

• suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
• specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
  —ESI/APCI (+) < 2 ppb
  —ESI/APCI (-) < 10 ppb
• lowest impurity profile: for interference-free baselines (test 2)
• microfiltered through 0.2 μm filter (test 3) to provide:
  —A long lifespan to filters and mechanical parts of HPLC systems
  ––reduced risk of column clogging
• packaged in borosilicate glass bottles for minimized metal ion contaminations
• lowest levels of trace metal impurities for a minimum metal ion adduct formation
  —<5 ppb
• lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Nota de preparación

Product filtered through a 0.2 μm filter

Nota de análisis

Evaporation Number: 1.9

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 3.0 mg/l
Water: ≤ 0.03 %
Color: ≤ 10 Hazen
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 225 nm): ≥ 50 %
Transmission (at 240 nm): ≥ 80 %
Transmission (from 265 nm): ≥ 98 %
Filtered by 0.2 µm filter

Información legal

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225 - H301 + H311 + H331 - H370
• Consejos de prudencia: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Código de clase de almacenamiento: 3 - Flammable liquids
• WGK: WGK 2
• Punto de inflamabilidad F: 49.5 °F - closed cup
• Punto de inflamabilidad C: 9.7 °C - closed cup