10127647001

Glucose-6-phosphate

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

• Synonym(s): D-Glucose 6-phosphate disodium salt hydrate, G-6-P-Na₂, Robison ester
• Empirical Formula (Hill Notation): C₆H₁₁Na₂O₉P · xH₂O
• CAS Number: 3671-99-6
• Molecular Weight: 304.10 (anhydrous basis)
• Beilstein: 5199009
• Número MDL: MFCD00150940
• ID de la sustancia en PubChem: 329748950

Properties

• formulario: solid
• mol peso: (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
• envase: pkg of 5 g
• manufacturer/tradename: Roche
• enviado en: ambient
• SMILES string: O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
• InChI key: UUWJZXLTPORJKW-WYFATIGWSA-L

Description

Descripción general

Disodium salt

Aplicación

Substrate for glucose-6-phosphatase.

Acciones bioquímicas o fisiológicas

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.

Componentes

77% glucose-6-P (enzymatic), 13% sodium, 8% water

Calidad

Contaminants: <0.2% glucose (enzymatic)

Variante de la fórmula

C₆H₁₁O₉PNa₂

Otras notas

For life science research only. Not for use in diagnostic procedures.

Safety Information

• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: does not flash
• Punto de inflamabilidad C: does not flash