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03777

Sigma-Aldrich

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid

BioUltra, for molecular biology, ≥99.0% (T)

Sinónimos:
Glycol ether diamine tetraacetic acid, Egtazic acid, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, EGTA
Fórmula lineal:
[-CH2OCH2CH2N(CH2CO2H)2]2
Número de CAS:
Peso molecular:
380.35
Beilstein:
1717370
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.25

Nivel de calidad

300

grado

for molecular biology

línea de producto

BioUltra

ensayo

≥99.0% (T)

formulario

powder

impurezas

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

residuo de ign.

≤0.05% (as SO4)

pérdida

≤1.0% loss on drying, 110 °C

mp

241 °C (dec.) (lit.)

solubilidad

0.1 M NaOH: 0.1 M at 20 °C, clear, colorless

trazas de anión

sulfate (SO42-): ≤50 mg/kg

trazas de catión

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorción

cut-off at 263 nm in 1 M NaOH at 0.1 M

SMILES string

OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChI key

DEFVIWRASFVYLL-UHFFFAOYSA-N

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Aplicación

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid can be used to study molecular biology, biochemicals, reagents and chelators. Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid has been used in a study that illustrated the response of the β-cyclodextrin-hemin complex in the induction of cucumber adventitious rooting through heme oxygenase-1-dependent mechanism and calcium signaling.
A chelating agent useful for the determination of calcium in the presence of magnesium.

Otras notas

Buffer component in dideoxy sequencing of RNA using reverse transcriptase.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

Certificado de origen

C.S. Hahn et al.
Methods in Enzymology, 180, 123-123 (1989)
Kennedy R Lees et al.
Stroke, 44(3), 580-584 (2013-02-09)
DP-b99, a lipophilic moderate-affinity chelator of zinc, was postulated to improve recovery after acute ischemic stroke. We evaluated the safety and therapeutic effects of DP-b99 in patients with acute hemispheric ischemic stroke. The Membrane-Activated Chelator Stroke Intervention trial was a
Andrew D Kane et al.
The Journal of physiology, 592(3), 475-489 (2013-11-20)
Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact with nitric oxide (NO) to provide an oxidant
Walter Marcotti et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(16), 5505-5514 (2014-04-18)
Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to
David R Whitfield et al.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 23(2), 141-148 (2014-06-24)
Depression is a common symptom in dementia with Lewy bodies (DLB), Parkinson disease dementia (PDD), and Alzheimer disease (AD), yet its molecular basis remains unclear and current antidepressants do not appear to be effective. Cerebral zinc has been implicated in

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