15527

Glicina

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• CAS Number: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 57647473
• NACRES: NA.21

Propiedades

• Nivel de calidad: 200
• Ensayo: 99-101% (based on anhydrous substance)
• Formulario: crystalline powder
• calidad: meets analytical specification of Ph. Eur., BP, USP
• técnicas: IR spectroscopy: suitable
• impurezas: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• residuo de ign.: ≤0.1% (as SO₄)
• pérdida: ≤0.2% loss on drying, 105 °C, 2 h
• color: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• trazas de anión: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• idoneidad: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• cadena SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Información sobre el gen: rat ... Grin2a(24409)

Descripción

Aplicación

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes.[1] It was used for biochemical and tolerance tests.[2]

Acciones bioquímicas o fisiológicas

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS.[3] During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria.[4] It also increases the in vitro development of porcine blastocysts when used along with glucose.[5]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)