199508

Sigma-Aldrich

Acridine Yellow G

Dye content 90 %

Empirical Formula (Hill Notation):
C15H15N3 · HCl
Número de CAS:
Peso molecular:
273.76
Colour Index Number:
46025
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

form

crystalline powder

composition

Dye content, 90%

application(s)

hematology: suitable
histology: suitable

solubility

water: 1 mg/mL, clear, yellow to orange

λmax

442 nm

ε (extinction coefficient)

44000 at 262-268 nm

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

room temp

SMILES string

Cl[H].Cc1cc2cc3cc(C)c(N)cc3nc2cc1N

InChI

1S/C15H15N3.ClH/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16;/h3-7H,16-17H2,1-2H3;1H

InChI key

BGLGAKMTYHWWKW-UHFFFAOYSA-N

Categorías relacionadas

Packaging

25 g in glass bottle

Biochem/physiol Actions

Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.

pictograms

Exclamation markHealth hazard

signalword

Warning

hazcat

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificado de Análisis

Certificado de origen

Qi Qi et al.
The Journal of biological chemistry, 287(9), 6113-6127 (2012-01-05)
Amplification of the epidermal growth factor receptor (EGFR), frequently expressed as a constitutively active deletion mutant (EGFRvIII), occurs commonly in glioblastoma multiformes (GBM). However, blockade of EGFR is therapeutically disappointing for gliomas with PTEN deletion. To search for small molecules...
T Pérez-Ruíz et al.
Analytical and bioanalytical chemistry, 375(5), 661-665 (2003-03-15)
A flow-injection configuration for the determination of formaldehyde is proposed. The method is based on the enhancing effect of formaldehyde on the oxidation of acridine yellow by bromate in acidic medium. The proposed procedure is simple, inexpensive, sensitive and suitable...
A H Uggla
Mutation research, 201(1), 229-239 (1988-09-01)
A comparison has been made between the ability of different acridine compounds to act as sensitizers for visible light (400-700 nm) induced chromosomal aberrations and sister-chromatid exchanges (SCE) in unsynchronized Chinese hamster ovary (CHO) cells. Cells were treated for 20...
Ashton acton
Gastrointestinal Hormones?Advances in Research and Application (2012)
Brotati Chakraborty et al.
The journal of physical chemistry. A, 114(51), 13313-13325 (2010-12-04)
Conventional spectroscopic tools such as absorption, fluorescence, and circular dichroism spectroscopy used in the study of photoinduced drug-protein interactions can yield useful information about ground-state and excited-state phenomena. However, photoinduced electron transfer (PET) may be a possible phenomenon in the...

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