Merck
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45661

Supelco

Strychnine

PESTANAL®, analytical standard

Sinónimos:
(−)-Strychnine
Empirical Formula (Hill Notation):
C21H22N2O2
Número de CAS:
Peso molecular:
334.41
Beilstein:
52979
Número de EC:
Número MDL:
ID de la sustancia en PubChem:

grado

analytical standard

Nivel de calidad

100

línea de producto

PESTANAL®

caducidad

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

284-286 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

formato

neat

SMILES string

[H][C@@]12CC(=O)N3c4ccccc4[C@]56CC[N@H]7CC(=CCO1)[C@]([H])(C[C@@H]57)[C@]2([H])[C@]36[H]

InChI

1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1

InChI key

QMGVPVSNSZLJIA-FVWCLLPLSA-N

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Descripción general

Strychnine is an alkaloid, available as a bioactive component in Semen Strychni, exhibiting analgesic, anti-inflammatory and anti-tumor effects. It is widely used in neurological research, treatment of genetic disorder nonketotic hyperglycinemia, treatment of stomach ailments, etc.

Aplicación

Strychnine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to electrospray ionization mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Convulsant; glycine receptor antagonist not associated with the NMDA receptor.

Información legal

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

pictogramas

Skull and crossbonesEnvironment

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Código de clase de almacenamiento

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Más documentos

Quotes and Ordering

Application of solid phase microextraction to the determination of strychnine in blood
Borroso.M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 816(1-2), 29-34 (2005)
The 100 Most Important Chemical Compounds: A Reference Guide (2005)
Determination of strychnine and brucine in rat plasma using liquid chromatography electrospray ionization mass spectrometry
Xu Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(2), 487-491 (2009)
Susanne Jonsson et al.
Neuropharmacology, 82, 69-75 (2014-04-02)
The ability of drugs of abuse to increase mesolimbic levels of dopamine is a characteristic associated with their rewarding effects. Exactly how these effects are produced by different substances is not as well characterised. Our previous work in rats has
Yan Lu et al.
The Journal of clinical investigation, 123(9), 4050-4062 (2013-08-28)
Neuropathic pain is characterized by mechanical allodynia induced by low-threshold myelinated Aβ-fiber activation. The original gate theory of pain proposes that inhibitory interneurons in the lamina II of the spinal dorsal horn (DH) act as "gate control" units for preventing

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