β-Estradiol 17-acetate

VETRANAL®, analytical standard

1,3,5(10)-Estratriene-3,17β-diol 17-acetate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate
Empirical Formula (Hill Notation):
Número de CAS:
Peso molecular:
Beilstein/REAXYS Number:
MDL number:
PubChem Substance ID:


analytical standard

product line




shelf life

limited shelf life, expiry date on the label


HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Pharmaceutical (small molecule)



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Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH


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Anna Höckerstedt et al.
Journal of lipid research, 43(3), 392-397 (2002-03-15)
It has been shown that estrogens need to be metabolized to their hydrophobic estrogen ester derivatives to act as antioxidants in lipoproteins. Data suggest that 17beta-estradiol (E(2)) becomes esterified in LCAT-induced reactions and the esters are transported from HDL particles...
J A Russell et al.
Journal of chromatography. B, Biomedical sciences and applications, 744(1), 157-163 (2000-09-14)
A rapid, sensitive reversed-phase high-performance liquid chromatographic method has been developed for the determination of in vitro release of 17beta-estradiol and its ester prodrug, 17beta-estradiol-3-acetate, from silicone intravaginal rings. Partial hydrolysis of the acetate under the aqueous conditions provided by...
Tomohiro Hikima et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 54(2), 155-160 (2002-08-23)
We have investigated the distribution of hydrolytic enzymes which metabolize beta-estradiol 17-acetate (EA) to beta-estradiol (E) in man and animal skins in vitro. The distribution of hydrolytic enzymes in human cadaver, hairless dog, rat and hairless mouse skin, was investigated...
B H Berg
Biochemistry international, 24(3), 527-533 (1991-06-01)
Adenylyl cyclase activity in the uterus of ovariectomized NMRI mice showed an increase of 87% four minutes after intraperitoneal administration of 17-beta-estradiol 17-beta-acetate in water solution, while in the liver of the same animals activity had decreased by 57%. At...
B H Berg
Biochemistry and molecular biology international, 29(5), 959-964 (1993-04-01)
When an adenylyl cyclase inhibitor, 2-deoxyadenosine 3'-phosphate, was administered together with 17-beta-estradiol 17-beta-acetate on ovariectomized Bom:NMRI mice, the short term effects of the hormone on the uterus aminoacyl-tRNA synthetase phosphatase and aminoacyl-tRNA synthetase activities were reversed, whereas the effect on...

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