Merck
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70079

Supelco

Myristic acid

analytical standard

Sinónimos:
Tetradecanoic acid, 1-Tridecanecarboxylic acid, NSC 5028, C14:0
Fórmula lineal:
CH3(CH2)12COOH
Número de CAS:
Peso molecular:
228.37
Beilstein:
508624
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

analytical standard

ensayo

≥99.5% (GC)

caducidad

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

250 °C/100 mmHg (lit.)

mp

52-54 °C (lit.)
53-56 °C

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

formato

neat

SMILES string

CCCCCCCCCCCCCC(O)=O

InChI

1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)

InChI key

TUNFSRHWOTWDNC-UHFFFAOYSA-N

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Descripción general

Myristic acid is an important bioactive component of Suanzaoren seed, which is one of the most commonly used Chinese medicine with therapeutic properties such as hypotensive, antihypoxia, hypnotic-sedative, antihyperlipidemia, and hypothermic effects.

Aplicación

Myristic acid may be used as an analytical reference standard for the quantification of the anayte in Ziziphus jujuba using high performance liquid chromatography with evaporative light scattering detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease .

Otras notas

Binding to serum albumin

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

nwg

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

A O Pedersen et al.
The Journal of biological chemistry, 263(21), 10236-10239 (1988-07-25)
Dialysis rate determinations of several fatty acids in the absence of albumin revealed that the myristate anion, like that of laurate, in aqueous solution, pH 7.5, is present as a monomer anion when the concentration is below 25 microM. Palmitate
Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction
Zhao.J, et al.
Journal of Chromatography A, 1108(2), 188-194 (2006)
Dalit Shental-Bechor et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17839-17844 (2012-08-01)
We present an integrated experimental and computational study of the molecular mechanisms by which myristoylation affects protein folding and function, which has been little characterized to date. Myristoylation, the covalent linkage of a hydrophobic C14 fatty acyl chain to the
Anja Meier et al.
Hepatology (Baltimore, Md.), 58(1), 31-42 (2012-12-06)
Chronic infection with the human hepatitis B virus (HBV) is a global health problem and a main cause of progressive liver diseases. HBV exhibits a narrow host range, replicating primarily in hepatocytes. Both host and hepatocyte specificity presumably involve specific
S Curry et al.
Biochimica et biophysica acta, 1441(2-3), 131-140 (1999-11-26)
Human serum albumin possesses multiple fatty acid binding sites of varying affinities, but the precise locations of these sites have remained elusive. The determination of the crystal structure of human serum albumin complexed with myristic acid recently revealed the positions

Artículos

GC Analysis of C2-C22 Free Fatty Acids on Nukol™

Separation of Methyl oleate; Caprylic acid; Heptanoic acid; Methyl decanoate; Methyl dodecanoate; Myristic acid; Methyl palmitate; Methyl palmitoleate; Methyl stearate; Methyl linoleate; Methyl linolenate; Acetic acid; Arachidic acid; Behenic acid; Propionic acid; Isobutyric acid; Valeric acid; Isovaleric acid; Isocaproic acid; Butyric acid

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