D8189

Sigma-Aldrich

Bis(1,3-dibutylbarbituric acid) trimethine oxonol

≥95% (HPLC)

Sinónimos:
DiBAC4(3)
Empirical Formula (Hill Notation):
C27H40N4O6
Número de CAS:
Peso molecular:
516.63
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

assay

≥95% (HPLC)

form

powder or solid

application(s)

hematology: suitable
histology: suitable

color

orange

solubility

DMF: soluble
DMSO: soluble

ε (extinction coefficient)

≥90000 at 490-496 nm in methanol

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

2-8°C

SMILES string

CCCCN(C(N(CCCC)C1=O)=O)C(C1=C/C=C/C2C(N(CCCC)C(N(CCCC)C2=O)=O)=O)=O

InChI

1S/C27H40N4O6/c1-5-9-16-28-22(32)20(23(33)29(26(28)36)17-10-6-2)14-13-15-21-24(34)30(18-11-7-3)27(37)31(25(21)35)19-12-8-4/h13-15,20H,5-12,16-19H2,1-4H3/b14-13+

InChI key

ATJCYSYHWGQAET-BUHFOSPRSA-N

Categorías relacionadas

Application

Bis(1,3-dibutylbarbituric acid) trimethine oxonol has been used for monitoring changes in the plasma membrane potential.
Application in high throughput screening.

Biochem/physiol Actions

Translational membrane potential dye that is redistributed in the cell as membrane potential changes.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificado de Análisis

Certificado de origen

T Bräuner et al.
Biochimica et biophysica acta, 771(2), 208-216 (1984-04-11)
The usefulness of a new voltage-sensitive fluorescent dye, the membrane permeant negatively charged oxonol dye diBA-C4-(3)-, was evaluated by measuring the membrane potentials of BICR/M1R-k and L cells with glass microelectrodes and simultaneously recording the fluorescence of the stained cells....
B Lee et al.
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Autocrine regulation of glioma cell proliferation via pHe-sensitive K(+) channels.
Honasoge A, et al.
American Journal of Physiology. Cell Physiology, 306, C493-C505 (2014)

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