H159

Supelco

Heroin

analytical standard, ≥98% (HPLC)

Sinónimos:
Diacetylmorphine
Empirical Formula (Hill Notation):
C21H23NO5
Número de CAS:
Peso molecular:
369.41
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

assay

≥98% (HPLC)

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

storage condition

desiccated

application(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white to beige

solubility

H2O: <0.2 mg/mL
DMSO: 5 mg/mL, clear
ethanol: 6 mg/mL
0.1 M HCl: <6.67 mg/mL

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)
Veterinary

format

neat

SMILES string

CN1CC[C@]23[C@H]4Oc5c(OC(C)=O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1

InChI key

GVGLGOZIDCSQPN-PVHGPHFFSA-N

General description

Heroin is a highly addictive illicit drug and opioid agonist, widely used in medical applications as an analgesic.

Application

Heroin may be used as a standard to determine the amount of heroin present in clandestine heroin samples using capillary zone electrophoresis (CZE) technique. Heroin may be used as an analytical reference standard for the quantification of the analyte in biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Heroin may be used as a standard to determine the amount of heroin present in clandestine heroin samples using capillary zone electrophoresis (CZE) technique.

pictograms

Skull and crossbones

signalword

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 1544PSN1 6.1 / PGI

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Joanne Neale et al.
Addiction (Abingdon, England), 114(4), 708-718 (2018-11-27)
Providing take-home naloxone (THN) to people who use opioids is an increasingly common strategy for reversing opioid overdose. However, implementation is hindered by doubts regarding the ability of people who use opioids to administer naloxone and respond appropriately to overdoses....
Ella Dilkes-Frayne et al.
The International journal on drug policy, 44, 164-173 (2017-06-06)
Addiction is generally understood to be characterised by a persistent pattern of regular, heavy alcohol and other drug consumption. Current models of addiction tend to locate the causes of these patterns within the body or brain of the individual, sidelining...
Julie Netherland et al.
Culture, medicine and psychiatry, 40(4), 664-686 (2016-06-09)
The past decade in the U.S. has been marked by a media fascination with the white prescription opioid cum heroin user. In this paper, we contrast media coverage of white non-medical opioid users with that of black and brown heroin...
Diacetylmorphine degradation to 6-monoacetylmorphine and morphine in cell culture: implications for in vitro studies
Hutchinson.RM, et al.
European Journal of Pharmacology, 453(1), 27-32 (2002)
Jennifer A Martin et al.
Nature communications, 10(1), 4140-4140 (2019-09-14)
Persistent transcriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. Opiate exposure reduces the density of dendritic spines on medium spiny neurons of the NAc;...
Protocolos
Separation of Heroin, analytical standard, ≥98% (HPLC); Cocaine hydrochloride, analytical standard; D-Amphetamine hemisulfate salt solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis; (±)-3,4-Methylenedioxymethamphetamine hydrochloride solution, analytical standard, for drug analysis, 1.0 mg/mL in methanol
Más información

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico

Redes sociales

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

Investigación. Desarrollo. Producción.

Somos un proveedor líder para la industria de Ciencias de la Vida con soluciones y servicios para investigación, desarrollo y producción biotecnológicos, y para desarrollo y producción de tratamientos farmacéuticos

© 2021 Merck KGaA, Darmstadt, Alemania y/o sus filiales. Todos los derechos reservados.

Queda estrictamente prohibida la reproducción sin permiso de cualquiera de los materiales de la página web.