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L5750

Sigma-Aldrich

Sodium dodecyl sulfate

92.5-100.5% based on total alkyl sulfate content basis

Sinónimos:
Lauryl sulfate sodium salt, Sodium lauryl sulfate, Dodecyl sulfate sodium salt, SDS, Dodecyl sodium sulfate
Fórmula lineal:
CH3(CH2)11OSO3Na
Número de CAS:
Peso molecular:
288.38
Beilstein:
3599286
EC Number:
MDL number:
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

Quality Level

description

anionic

assay

92.5-100.5% based on total alkyl sulfate content basis

mol wt

288.38 g/mol

aggregation number

62

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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Categorías relacionadas

Application

Sodium dodecyl sulfate has been used:
  • to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
  • to perform SDS–PAGE of yeast tubulin
  • as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)

Anionic detergent

Packaging

1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Quality

Predominantly (approx. 70%) C12; lauryl sulfate, sodium salt; balance consists of higher homologs.

Analysis Note

Actual composition given on label

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 2

Flash Point F

338.0 °F

Flash Point C

170 °C

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificado de Análisis

Certificado de origen

The two alpha-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro
Bode CJ, et al.
EMBO Reports, 4(1), 94-99 (2003)
Resilient Ribonucleases
RNA Methodologies (2010)
Two antioxidative lactobacilli strains as promising probiotics
Kullisaar T, et al.
International Journal of Food Microbiology, 72(3), 215-224 (2002)
Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
Fontanay S, et al.
Journal of Ethnopharmacology, 120(2), 272-276 (2008)
Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins
Lin P Y, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 259, 168-175 (2017)

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