meets USP testing specifications

4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide
Empirical Formula (Hill Notation):
Número de CAS:
Peso molecular:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


meets USP testing specifications

Featured Industry

Pharmaceutical (small molecule)

storage temp.


SMILES string




InChI key


Gene Information

human ... PTGS1(5742), PTGS2(5743)
rat ... Alox5(25290)

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1, 5, 10 g in glass bottle

Biochem/physiol Actions

Cyclooxygenase inhibitor.


Skull and crossbonesHealth hazard



Target Organs

Gastrointestinal tract

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


UN 2811 6.1 / PGIII

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Andres Lust et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 47-54 (2012-10-23)
The aim of this study was to gain understanding about the effects of different solid-state forms of a poorly water-soluble piroxicam on drug dissolution and oral bioavailability in rats. Three different solid-state forms of piroxicam were studied: anhydrate I (AH)...
D Gerber
Drug intelligence & clinical pharmacy, 21(9), 707-710 (1987-09-01)
During the approximately five years (1981-86) that piroxicam has been available in South Africa, the Medicines Safety Centre has received 31 reports of adverse reactions associated with this drug. Among these are two reactions not previously recorded in the literature...
Stéphane Lemaître et al.
Bioorganic & medicinal chemistry, 17(6), 2607-2622 (2009-03-06)
Based on the definition of a 5-HT(4) receptor antagonist pharmacophore, a series of pyrrolo[1,2-a]thieno[3,2-e] and pyrrolo[1,2-a]thieno[2,3-e] pyrazine derivatives were designed, prepared, and evaluated to determine the properties necessary for high-affinity binding to 5-HT(4) receptors. The compounds were synthesized by substituting...
K Nezvalová-Henriksen et al.
BJOG : an international journal of obstetrics and gynaecology, 120(8), 948-959 (2013-03-16)
To investigate the individual effects of ibuprofen, diclofenac, naproxen, and piroxicam on pregnancy outcome. Cohort study. Norwegian population. A total of 90 417 women and singleton child pairs. The Norwegian Mother and Child Cohort Study and Medical Birth Registry of...
Mariana P Arce et al.
Journal of medicinal chemistry, 52(22), 7249-7257 (2009-10-28)
Novel multifunctional compounds have been designed, synthesized, and evaluated as potential drugs for the treatment of Alzheimer's disease (AD). With an L-glutamic moiety as a suitable biocompatible linker, three pharmacophoric groups were joined: (1) an N-benzylpiperidine fragment selected to inhibit...

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