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PHR1136

Supelco

Guaiacol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:
Catechol monomethyl ether, 2-Methoxyphenol, Pyrocatechol monomethyl ether
Fórmula lineal:
(CH3O)C6H4OH
Número de CAS:
Peso molecular:
124.14
Beilstein:
508112
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.24

Nivel de calidad

300

grado

certified reference material
pharmaceutical secondary standard

Agency

traceable to Ph. Eur. Y0000619
traceable to USP 1300004

densidad de vapor

4.27 (vs air)

presión de vapor

0.11 mmHg ( 25 °C)

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refracción

n20/D 1.543 (lit.)

bp

205 °C (lit.)

mp

26-29 °C (lit.)

densidad

1.129 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

SMILES string

COc1ccccc1O

InChI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChI key

LHGVFZTZFXWLCP-UHFFFAOYSA-N

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Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Guaiacol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and electroanalytical techniques.

Acciones bioquímicas o fisiológicas

Guaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB3328 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

194.0 °F - closed cup

Punto de inflamabilidad C

90 °C - closed cup

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Electroanalytical determination of codeine in pharmaceutical preparations.
Garrido JMPJ, et al.
Analytical Letters, 35(15), 2487-2498 (2002)
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup.
Grosa G, et al.
Journal of Pharmaceutical and Biomedical Analysis, 41(3), 798-803 (2006)
K M Pruitt et al.
Analytical biochemistry, 191(2), 278-286 (1990-12-01)
Because of the important biological functions of peroxidases, there is growing interest in the measurement of their concentrations in various secretions. At present, there is no standard method which allows for comparisons in reported activities. This report describes procedures which
Joel D Mainland et al.
Nature neuroscience, 17(1), 114-120 (2013-12-10)
Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function.
Chien-Yun Hsiang et al.
Food chemistry, 136(1), 170-177 (2012-09-29)
Ginger is a commonly used spice with anti-inflammatory potential. Colitis is the common pathological lesion of inflammatory bowel diseases. In this study, we investigated the therapeutic effects of ginger and its component zingerone in mice with 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced

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