PHR1616

Granisetron Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Granisetron hydrochloride, 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride
• Empirical Formula (Hill Notation): C₁₈H₂₄N₄O· HCl
• CAS Number: 107007-99-8
• Molecular Weight: 348.87
• Número MDL: MFCD01747034
• ID de la sustancia en PubChem: 329823512
• NACRES: NA.24

Properties

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. Y0000396; traceable to USP 1298106
• CofA: current certificate can be downloaded
• envase: pkg of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-30°C
• SMILES string: Cl.CN1[C@H]2CCC[C@@H]1C[C@@H](C2)NC(=O)c3nn(C)c4ccccc34
• InChI: 1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
• InChI key: QYZRTBKYBJRGJB-WQTKJZBYSA-N

Description

Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Granisetron Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, and human plasma samples employed in bioequivalence studies by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Envase

500 mg

Acciones bioquímicas o fisiológicas

Granisetron hydrochloride is a serotonin 5-HT₃ receptor antagonist and antiemetic.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA4875 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable