PHR1623

Supelco

Galantamine Hydrobromide

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:
Galantamine hydrobromide, Galanthamine hydrobromide
Empirical Formula (Hill Notation):
C17H21NO3 · HBr
Número de CAS:
Peso molecular:
368.27
EC Number:
MDL number:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to PhEur Y0001279
traceable to USP 1287755

SMILES string

[H][C@]1(O2)C[C@@H](O)C=C[C@@]13C4=C2C(OC)=CC=C4CN(C)CC3.Br

InChI

1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChI key

QORVDGQLPPAFRS-XPSHAMGMSA-N

¿Está buscando productos similares? Visit Guía de comparación de productos

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Galantamine Hydrobromide, a reversible, competitive acetyl cholinesterase inhibitor, is suggested for the remedy of mild to moderate dementia of the Alzheimer′s type.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Galantamine Hydrobromide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1681 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Skull and crossbones

signalword

Danger

hcodes

hazcat

Acute Tox. 3 Oral

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificado de Análisis

Certificado de origen

Pharmacokinetics and bioequivalence studies of galantamine hydrobromide dispersible tablet in healthy male Chinese volunteers.
Zhang LJ, et al.
Drug Development and Industrial Pharmacy, 33(3) (2007)
Quantitative determination of galantamine hydrobromide in pharmaceutical dosage form by RP-high performance liquid chromatography.
Krupesh BP, et al.
Journal of Chemical and Pharmaceutical Research, 2(2), 36-43 (2010)
Improving method capability of a drug substance HPLC assay.
Dejaegher B, et al.
Journal of Pharmaceutical and Biomedical Analysis, 42(2), 155-170 (2006)
Oil-in-water microemulsion high performance liquid chromatographic analysis of pharmaceuticals.
Marsh A, et al.
Chromatographia, 59(9), 531-542 (2004)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico