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T4375

Sigma-Aldrich

Tetrazolium Blue Chloride

used in colorimetric determination of reducing compounds

Sinónimos:
Blue Tetrazolium chloride, TZ, 3,3′-(3,3′-Dimethoxy[1,1′-biphenyl]-4,4′-diyl)-bis(2,5-diphenyl-2H-tetrazolium) dichloride, BTC, 3,3′-Dianisole-4,4′-bis(3,5-diphenyltetrazolium chloride)
Empirical Formula (Hill Notation):
C40H32Cl2N8O2
Número de CAS:
Peso molecular:
727.64
Beilstein:
3894077
Número de EC:
Número MDL:
ID de la sustancia en PubChem:

Nivel de calidad

200

formulario

powder

mp

255 °C (dec.) (lit.)

solubilidad

methanol: 50 mg/mL, clear

application(s)

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

SMILES string

[Cl-].[Cl-].COc1cc(ccc1-[n+]2nc(nn2-c3ccccc3)-c4ccccc4)-c5ccc(c(OC)c5)-[n+]6nc(nn6-c7ccccc7)-c8ccccc8

InChI

1S/C40H32N8O2.2ClH/c1-49-37-27-31(23-25-35(37)47-43-39(29-15-7-3-8-16-29)41-45(47)33-19-11-5-12-20-33)32-24-26-36(38(28-32)50-2)48-44-40(30-17-9-4-10-18-30)42-46(48)34-21-13-6-14-22-34;;/h3-28H,1-2H3;2*1H/q+2;;/p-2

InChI key

MUUHXGOJWVMBDY-UHFFFAOYSA-L

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Categorías relacionadas

Aplicación

Tetrazolium blue chloride (BTC) is a colorless tetrazolium compound that upon reduction forms a colored diformazan. The reactivity has been applied to the analysis of reducing compounds including the nanomolar detection of reducing sugars and carbidopa and methyldopa. BTC has been used for histological staining of mouse coronal brain sections and rat brain sections. In combination with 4-nitrocatechol, tetrazolium blue chloride forms a ternary complex with molybdenum(VI) for extraction and spectrophotometric determination of molybdenum. It has also been used to stain Francisella tularensis cells for tularemic microagglutination test.

Envase

1, 5, 10, 25 g in glass bottle

pictogramas

Health hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Carc. 1B

Código de clase de almacenamiento

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

Preparation of a new tetrazolium salt which yields a blue pigment on reduction and its use in the demonstration of enzymes in normal and neoplastic tissues.
A M RUTENBURG et al.
Cancer research, 10(2), 113-121 (1950-02-01)
J J Li et al.
Neuroscience, 167(3), 665-677 (2010-03-09)
We reported previously that amoeboid microglial cells (AMC) in the developing brain exhibited endothelins (ETs) expression which diminished with advancing age and was undetected in microglia in the more mature brain. This study sought to explore if microglia in the
Sensitive colorimetric assay of carbidopa and methyldopa using tetrazolium blue chloride in pharmaceutical products.
Issopoulos, P.B.
International Journal of Clinical Pharmacy, 11, 213-217 (1989)
[Development of a novel Francisella tularensis antigen stained with tetrazolium-blue for tularemia microagglutination test].
Celebi B
Mikrobiyoloji bulteni (2013)
Ternary complex of molybdenum(VI) with 4-nitrocatechol and tetrazolium blue chloride and Its application to extraction-spectrophotometric analysis of ferrous metallurgy products.
Dimitrov., A.N., et al.
Journal of Analytical Chemistry, 62, 122-125 (2007)

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