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Merck

217565

Sigma-Aldrich

Barium chloride dihydrate

ACS reagent, ≥99%

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Fórmula empírica (notación de Hill):
BaCl2 · 2H2O
Número de CAS:
Peso molecular:
244.26
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NB.24

grade

ACS reagent

Quality Level

assay

≥99%

form

powder, crystals or chunks

impurities

≤0.005% insolubles
≤0.005% oxidizers

loss

14.0-16.0% loss on drying

pH

5.2-8.2 (25 °C, 5%)

cation traces

Ca: ≤0.05%
Fe: ≤2 ppm
K: ≤0.0025%
Na: ≤0.005%
Sr: ≤0.1%
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

O.O.Cl[Ba]Cl

InChI

1S/Ba.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2

InChI key

PWHCIQQGOQTFAE-UHFFFAOYSA-L

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Categorías relacionadas

Application

Barium chloride dihydrate has been used:
  • in patch-clamp electrophysiological studies to block subthreshold-activated potassium channels
  • as an inward rectifier potassium (Kir) channel blocker to study the role of the channel by measuring the microglial membrane currents in response to voltage ramp stimuli after ATP injection
  • to prepare the stock solution to make artificial cerebrospinal fluid (aCSF)

Biochem/physiol Actions

Barium chloride is a potassium ion channel blocker. It is considered toxic. Barium chloride prevents the D2-like receptor-mediated hyperpolarisation of spinal central pattern generator (CPG) neurons

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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