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31437

Sigma-Aldrich

Sodium bicarbonate

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.7%

Sinónimos:
Sodium hydrogen carbonate
Fórmula lineal:
NaHCO3
Número de CAS:
Peso molecular:
84.01
Beilstein:
4153970
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.85

Nivel de calidad

200

grado

ACS reagent
puriss. p.a.

Agency

reag. Ph. Eur.

ensayo

≥99.7%

formulario

powder

impurezas

≤0.0005% ammonium (NH4)
≤0.003% S-compounds (as SO4)
≤0.005% I red. matters (as SO2)
≤0.015% in water insoluble matters

pH

≤8.6 (20 °C, 5%)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubilidad

H2O: 0.5 g/10 mL, clear, colorless
water: soluble 50 g/L

densidad

2.16 g/mL at 25 °C (lit.)

trazas de anión

chloride (Cl-): ≤10 mg/kg
phosphate (PO43-): ≤10 mg/kg

trazas de catión

As: 2 ppm (MHS-AAS)
Ca: ≤100 ppm
Cd: ≤5 ppm
Co: ≤50 ppm
Cu: ≤5 ppm
Fe: ≤5 ppm
K: ≤50 ppm
Mg: ≤50 ppm
Ni: ≤50 ppm
Pb: ≤5 ppm
Zn: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

idoneidad

complies for appearance of solution

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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Descripción general

Sodium bicarbonate is widely used as a physiological buffer. The pKa for bicarbonate ↔ carbonic acid reaction is 6.37. The pKa for bicarbonate ↔ carbonate reaction is 10.25.

Aplicación

Sodium bicarbonate may be used to maintain 7.4pH in Iscove′s modified Dulbecco′s medium for growth of murine hybridoma cell culture. It may be employed as a component of RPMI-1640 liquid medium in a study.

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Más documentos

Quotes and Ordering

D W Denning et al.
The Journal of antimicrobial chemotherapy, 40(3), 401-414 (1997-10-24)
Given the increased choice of therapeutic agents and the rising incidence of serious invasive disease, it is important that reliable in-vitro methods for detecting antifungal drug resistance in Aspergillus spp. are developed. Six clinical isolates of Aspergillus fumigatus, obtained from
S S Ozturk et al.
Biotechnology and bioengineering, 39(4), 418-431 (1992-02-20)
The influence of ammonia and lactate on cell growth, metabolic, and antibody production rates was investigated for murine hybridoma cell line 163.4G5.3 during batch culture. The specific growth rate was reduced by one-half in the presence of an initial ammonia
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal

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