Merck
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30970

Sigma-Aldrich

Sodium deoxycholate

BioXtra, ≥98.0% (dry matter, NT)

Synonym(s):
3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4
CAS Number:
Molecular Weight:
414.55
Beilstein:
3581950
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.21

origen biológico

ox bile

Nivel de calidad

descripción

anionic

Línea del producto

BioXtra

ensayo

≥98.0% (dry matter, NT)

formulario

powder

actividad óptica

[α]20/D +44±2°, c = 2% in H2O

mol peso

micellar avg mol wt 1200-5000

número de agregación

3-12

technique(s)

DNA purification: suitable
RNA purification: suitable
electrophoresis: suitable

impurezas

≤1% cholic acid (HPLC)
≤6% water

CMC

2-6 mM (20-25°C)

solubilidad

water: soluble 1 gm in 10 ml, clear, colorless to very faintly yellow

trazas de catión

Ca: ≤500 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤10 mg/kg
Zn: ≤5 mg/kg

HLB

16

grupo funcional

carboxylic acid

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

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Aplicación

Sodium deoxycholate has been used for preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.

Envase

25, 100, 500 g in poly bottle

Acciones bioquímicas o fisiológicas

Sodium deoxycholate is a bile salt that stimulates the apical to basolateral accumulation of epirubicin in Caco-2 cells as well as increased serosal absorption of epirubicin in the rat jejunum and ileum. Sodium deoxycholate dissociates histones II from DNA as well as causes lysis of the viral membrane.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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