30970

Sodium deoxycholate

BioXtra, ≥98.0% (dry matter, NT)

• Synonym(s): 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• Empirical Formula (Hill Notation): C₂₄H₃₉NaO₄
• CAS Number: 302-95-4
• Molecular Weight: 414.55
• Beilstein: 3581950
• Número de EC: 206-132-7
• Número MDL: MFCD00064139
• ID de la sustancia en PubChem: 57648497
• NACRES: NA.21

Properties

• origen biológico: ox bile
• Nivel de calidad: 300
• descripción: anionic
• Línea del producto: BioXtra
• ensayo: ≥98.0% (dry matter, NT)
• formulario: powder
• actividad óptica: [α]20/D +44±2°, c = 2% in H₂O
• mol peso: micellar avg mol wt 1200-5000
• número de agregación: 3-12
• technique(s): DNA purification: suitable; RNA purification: suitable; electrophoresis: suitable
• impurezas: ≤1% cholic acid (HPLC); ≤6% water
• CMC: 2-6 mM (20-25°C)
• solubilidad: water: soluble 1 gm in 10 ml, clear, colorless to very faintly yellow
• trazas de catión: Ca: ≤500 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; Mg: ≤10 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg; Zn: ≤5 mg/kg
• HLB: 16
• grupo funcional: carboxylic acid
• SMILES string: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
• InChI key: FHHPUSMSKHSNKW-SMOYURAASA-M

Description

Aplicación

Sodium deoxycholate has been used for preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.

Envase

25, 100, 500 g in poly bottle

Acciones bioquímicas o fisiológicas

Sodium deoxycholate is a bile salt that stimulates the apical to basolateral accumulation of epirubicin in Caco-2 cells as well as increased serosal absorption of epirubicin in the rat jejunum and ileum. Sodium deoxycholate dissociates histones II from DNA as well as causes lysis of the viral membrane.

Safety Information

• pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves