Merck
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43816

Sigma-Aldrich

DL-Dithiothreitol solution

BioUltra, for molecular biology, ~1 M in H2O

Synonym(s):
(±)-threo-1,4-Dimercapto-2,3-butanediol solution, DTT
Empirical Formula (Hill Notation):
C4H10O2S2
CAS Number:
Molecular Weight:
154.25
Beilstein:
1719757
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.25

grado

for molecular biology

Nivel de calidad

200

línea de producto

BioUltra

formulario

liquid

concentración

~1 M in H2O

impurezas

DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected

pH

2.7-5.0

densidad

1.04 g/mL at 20 °C

absorción

cut-off at 330 nm

idoneidad

in accordance for filter test

temp. de almacenamiento

2-8°C

SMILES string

O[C@H](CS)[C@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChI key

VHJLVAABSRFDPM-QWWZWVQMSA-N

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Aplicación

DL-dithiothreitol solution has been used:
  • in the treatment of intestinal explants
  • in homogenate preparation of gill cells for enzymatic assays
  • in western blotting
  • in transglutaminase activity

Acciones bioquímicas o fisiológicas

DL-dithiothreitol (DTT) is used in a chemical debonding technique, that helps to remove bacteria from biofilms. It can change the structural stability of the GABA(B) (gamma-aminobutyric acid) receptor by disabling the disulfide bonds between four cysteine residues positioned in the GABA(B1(a)) receptor structure.

pictogramas

Corrosion

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Eye Dam. 1 - Skin Irrit. 2

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificate of Analysis

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Certificate of Origin

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