Merck
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50046

Sigma-Aldrich

Glicina

BioUltra, for molecular biology, ≥99.0% (NT)

Synonym(s):
Glicocola, Ácido aminoacético, Ácido aminoetanoico
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

for molecular biology

Quality Level

product line

BioUltra

Assay

≥99.0% (NT)

form

crystalline

impurities

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤200 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

NCC(O)=O

λ

1 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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grade

for molecular biology

grade

-

grade

-

grade

-

product line

BioUltra

product line

ReagentPlus®

product line

-

product line

-

assay

≥99.0% (NT)

assay

≥99% (HPLC)

assay

99.7-101% (calc. to the dried substance)

assay

≥99%

form

crystalline

form

powder

form

crystalline powder

form

powder

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

≤0.01% Ammonia

impurities

≤0.001% heavy metals (as Pb), ≤0.02% ammonium (NH4), ≤0.1% water (Karl Fischer), ≤1.0% ninhydrin-positive substances

impurities

≤0.01% Insoluble matter

color

white

color

white to off-white

color

-

color

white to off-white

Application

La glicina se ha utilizado como componente de la mezcla de extracción vírica para la extracción de los adenovirus.

Biochem/physiol Actions

La glicina es un aminoácido no esencial. Está implicada en la síntesis de purinas, serina y porfirinas. Los canales activados por glicina median el flujo de entrada de calcio a través de las membranas celulares. También actúa como agonista competitivo del glutamato en la unión a los receptores NMDA (N-metil-D-aspartato). En las células cancerosas, podría estar aumentada la síntesis de glicina debido al aumento de la demanda del aminoácido.
Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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