Todas las fotos(1)

57600

Sigma-Aldrich

Interleukin-2 human

recombinant, expressed in E. coli, ~10000 U/mL

Sinónimos:
IL-2, hIL-2, TCGF
Número de CAS:
Número MDL:
NACRES:
NA.32

Nivel de calidad

100

origen biológico

human

recombinante

expressed in E. coli

formulario

liquid

mol peso

Mr ~15500

envase

vial of 1 mL

concentración

~10000 U/mL

color

colorless

Nº de acceso UniProt

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... IL2(3558)

Categorías relacionadas

Acciones bioquímicas o fisiológicas

Promotes the growth of IL-2 dependent lymphocytes. Amino acid sequence of IL-2.

Envase

One vial contains 10′000 Units

Precaución

Stable at −20 °C; prepare appropriate aliquots and avoid repeated freezing and thawing, since aggregation may occur resulting in apparent loss of activity.

Definición de unidad

1 U corresponds to the unit activity in the colorimetric MTT-assay with CTLL-2 cells.

Forma física

Clear; colorless solution in Dulbecco-PBS; containing 1 mg BSA/mL.

Otras notas

Sales restrictions may apply.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
Nabil Ahmed et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(15), 1688-1696 (2015-03-25)
The outcome for patients with metastatic or recurrent sarcoma remains poor. Adoptive therapy with tumor-directed T cells is an attractive therapeutic option but has never been evaluated in sarcoma. We conducted a phase I/II clinical study in which patients with
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27

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