Merck
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93659

Sigma-Aldrich

L-Tryptophan

BioUltra, ≥99.5% (NT)

Sinónimos:
L-α-Amino-3-indolepropionic acid, (S)-2-Amino-3-(3-indolyl)propionic acid
Empirical Formula (Hill Notation):
C11H12N2O2
Número de CAS:
Peso molecular:
204.23
Beilstein:
86197
Número de EC:
Número MDL:
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.26

línea de producto

BioUltra

Nivel de calidad

100

ensayo

≥99.5% (NT)

formulario

powder or crystals

actividad óptica

[α]20/D −31.5±1°, c = 1% in H2O

impurezas

insoluble matter, passes filter test

residuo de ign.

≤0.1%

pérdida

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

280-285 °C (dec.) (lit.)

solubilidad

0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow

trazas de anión

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

trazas de catión

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorción

cut-off at 326 nm in 0.5 M HCl at 0.5 M

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChI key

QIVBCDIJIAJPQS-VIFPVBQESA-N

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Aplicación

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.

Acciones bioquímicas o fisiológicas

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Otras notas

Amino acid precursor of serotonin and melatonin
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 93659.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
In tryptophan-substituted Sephadex® and Sepharose® for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms.

Información legal

Sephadex is a registered trademark of Cytiva
Sepharose is a registered trademark of Cytiva

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

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Certificado de origen

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Más documentos

Presupuestos y pedidos

M A Vijayalakshmi et al.
Journal of chromatography, 177(2), 201-208 (1979-09-21)
The adsorption of tyrosine, tryptophan and some related compounds on tryptophan and tryptophanyltryptophan gels is similar to but much stronger than that observed with the parent gel Sephadex G-25. The adsorption has been attributed mainly to charge transfer or redistribution
CRC Handbook of Microbiology, 4, 1-1 (1974)
Long-lasting effect of perinatal exposure to L-tryptophan on circadian clock of primary cell lines established from male offspring born from mothers fed on dietary protein restriction.
Nascimento E
PLoS ONE, 8(2), 1-14 (2013)
T. Hine et al.
Electrophoresis ?83, 541-541 (1984)
Variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols
Jae HeeJung and Jung EunLee
Journal of Aerosol Science, 65, 101-110 (2013)

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