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Merck

95209

Sigma-Aldrich

Ácido L-ascórbico

BioUltra, ≥99.5% (RT)

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Sinónimos:
Ácido L-treoascórbico, Factor antiescorbútico, Vitamina C
Fórmula empírica (notación de Hill):
C6H8O6
Número de CAS:
Peso molecular:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79

biological source

synthetic

Quality Level

product line

BioUltra

assay

≥99.5% (RT)

form

powder or crystals

impurities

insoluble matter, passes filter test

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, 20 °C (HV)

color

white to off-white

pH

1.0-2.5 (25 °C, 1 M in H2O)

mp

190-194 °C (dec.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorption

cut-off at 306 nm in H2O at 1 M

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

L-Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. It is naturally present in a variety of foods such as citrus fruits and vegetables. It is present only in minimal amount in milk.

Application

L-Ascorbic acid has been used as an antioxidant supplement in incubation solution for dissected and sliced brain sections. It has also been used as a supplement in phosphate-buffered saline (PBS) wash buffer during oxidative GFP chromophore formation.

Biochem/physiol Actions

L-Ascorbic acid (Vitamin C) acts as a potential anti-oxidant and reducing agent. It prevents bacterial mutagenesis induced by N-nitroso compounds. In plants, vitamin C elicits several cellular processes such as growth, apoptosis, pathogen responses, hormone responses, flowering and senescence, and protection against environmental stresses. Vitamin C deficiency is associated with the development of scurvy, prominent - gingivitis, perifollicular hemorrhages, poor wound healing, petechiae and ecchymosis.

Other Notes

Denaturation of proteins; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABE.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Calcium Imaging Techniques In Vitro to Explore the Role of Dendrites in Signaling Physiological Action Potential Patterns
Neuromethods, 165-187 (2012)
F C Brown et al.
Neurochemical research, 3(3), 357-366 (1978-06-01)
Under conditions that are optimum for DbetaH, ascorbic acid denatures serum albumin, gamma-globulin, catalase, and DbetaH. With ascrobate plus Cu2+, the proteins are almost completely destroyed. Pyrazole protects DbetaH and albumin, but not catalase. Superoxide dismutase (SOD) is not denatured
Calcium Imaging Techniques In Vitro to Explore the Role of Dendrites in Signaling Physiological Action Potential Patterns
Bonnan A, et al.
The Journal of applied nutrition (1953)
Inhibition by L-ascorbate of bacterial mutagenesis induced by two N-nitroso compounds
Guttenplan JB
Nature, 268(5618), 368-368 (1977)
L-Ascorbate biosynthesis in higher plants: the role of VTC2
Linster CL and Clarke SG
Trends in Plant Science, 13(11), 567-573 (2008)

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