Merck
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A1470

Sigma-Aldrich

Bovine Serum Albumin

lyophilized powder, low endotoxin, Cohn Analog, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

Sinónimos:
Albumin bovine serum, Bovine albumin, BSA
Número de CAS:
Número de EC:
Número MDL:
NACRES:
NA.27

Nivel de calidad

200

origen biológico

bovine

línea de producto

BioReagent

ensayo

≥98% (agarose gel electrophoresis)

formulario

lyophilized powder

mol peso

~66 kDa

purificado por

heat shock fractionation

envase

poly bottle of

origen

USA origin

technique(s)

cell culture | mammalian: suitable

impurezas

≤20 ppm Pb
≤3 EU/mg endotoxin

pH

7

solubilidad

water: soluble (40 mg/ml)

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

Gene Information

bovine ... ALB(280717)

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Categorías relacionadas

Aplicación

Recommended as a growth-enhancing supplement for cell culture.
Select the right albumin for your application with the Albumin Selection Guide

Envase

5 kg in fiber drum
10, 25, 100 g in poly bottle

Acciones bioquímicas o fisiológicas

Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.

Características y beneficios

  • Tested for use in cell culture
  • Low endotoxin

Nota de preparación

Manufactured by a novel process that maintains the lipid and growth factor characteristics of cold-ethanol precipitated albumins.
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.

Información legal

Cohn Analog is a trademark of Proliant, Inc.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Akshay Shekhar et al.
Scientific reports, 8(1), 9944-9944 (2018-07-04)
Rapid impulse propagation is a defining attribute of the pectinated atrial myocardium and His-Purkinje system (HPS) that safeguards against atrial and ventricular arrhythmias, conduction block, and myocardial dyssynchrony. The complex transcriptional circuitry that dictates rapid conduction remains incompletely understood. Here
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Holger Bronger et al.
Oncology letters, 13(6), 4224-4230 (2017-06-11)
Cathepsin B (CTSB) is a lysosomal cysteine protease that has been linked to the progression of breast cancer, for example by activation of other proteases and tumor-promoting cytokines, thereby supporting tumor invasion and metastasis. Previously, it was shown that CTSB
Marcos V A S Navarro et al.
PLoS biology, 9(2), e1000588-e1000588 (2011-02-10)
The bacterial second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP) has emerged as a central regulator for biofilm formation. Increased cellular c-di-GMP levels lead to stable cell attachment, which in Pseudomonas fluorescens requires the transmembrane receptor LapD. LapD exhibits a
Manoj K Pandey et al.
Molecular pharmacology, 75(3), 525-533 (2008-12-24)
The aim of the current study is to determine whether butein (3,4,2',4'-tetrahydroxychalcone) exhibits antiproliferative effects against tumor cells through suppression of the signal transducer and activator of transcription 3 (STAT3) activation pathway. We investigated the effects of butein on constitutive

Artículos

Albumin in Cell Culture

This page segues to comprehensive insights on how serum albumin and other important cell culture components affect the performance of serum-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of albumin. These insights may also be applied to ex vivo and tissue engineering applications.

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