A3221

Iodoacetamide

Single use vial of 56 mg

• Synonym(s): 2-Iodoacetamide, Monoiodoacetamide, alpha-Iodoacetamide
• Linear Formula: ICH₂CONH₂
• CAS Number: 144-48-9
• Molecular Weight: 184.96
• Beilstein: 1739080
• Número de EC: 205-630-1
• Número MDL: MFCD00008028
• ID de la sustancia en PubChem: 24890731
• NACRES: NA.56

Properties

• Nivel de calidad: 200
• ensayo: ≥99% (HPLC)
• formulario: powder
• envase: vial of 56 mg (Single use)
• mp: 92-95 °C (lit.)
• solubilidad: H₂O: soluble 50 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: 2-8°C
• SMILES string: NC(=O)CI
• InChI: 1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
• InChI key: PGLTVOMIXTUURA-UHFFFAOYSA-N

Description

Aplicación

Iodoacetamide may be used as an alkylating reagent for cysteine residues in peptide sequencing and peptide/protein analytical analysis. It may be used in 2-D protein electrophoresis to reduce streaking and improve resolution by eliminating artifacts that could result from disulfide formation during electrophoresis. By virtue of its reaction with cysteine, iodoacetamide is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease. Iodoacetamide may be used in disulfide stress research.

Acciones bioquímicas o fisiológicas

Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease.

Envase

Packaged in sealed ampules

Información legal

Technology developed in partnership with Proteome Systems^™

Proteome Systems is a trademark of Proteome Systems Ltd

Safety Information

• pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H301 - H317 - H334 - H413
• Consejos de prudencia: P261 - P264 - P273 - P280 - P301 + P310 - P302 + P352
• Clasificaciones de peligro: Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
• Código de clase de almacenamiento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges