L-Arginine monohydrochloride

(S)-(+)-Arginine hydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
Número de CAS:
Peso molecular:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

biological source

non-animal source




crystalline powder




cell culture | mammalian: suitable


endotoxin, heavy metals, residual solvents, tested


H2O: 100 mg/mL


1.42 g/cm3 at 20 °C

anion traces

chloride (Cl-): 16.58-17.00%
sulfate (SO42-): ≤0.020%

cation traces

As: ≤1.0 ppm
NH4+: ≤0.02%
heavy metals: ≤10 ppm

Featured Industry

Pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

SMILES string




InChI key


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General description

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.


L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.


13 - Non Combustible Solids

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificado de Análisis

Certificado de origen

Ilaria Canobbio et al.
The Biochemical journal, 462(3), 513-523 (2014-07-02)
Alzheimer's disease is associated with the accumulation of Aβ (amyloid β)-peptides in the brain. Besides their cytotoxic effect on neurons, Aβ-peptides are thought to be responsible for the atherothrombotic complications associated with Alzheimer's disease, which are collectively known as cerebrovascular...
N E Paul et al.
Bio-medical materials and engineering, 25(3), 289-297 (2015-09-26)
Adipose tissue engineering is a promising solution for the reconstruction of soft tissue defects. An insufficient neovascularisation within the scaffolds that leads to necrosis and tissue loss is still a major shortcoming of current tissue engineering attempts. Biomaterials, which release...
Carolina Di Somma et al.
Endocrine, 49(2), 492-502 (2014-11-10)
The aim of the study is to clarify the relationship between adipose tissue dysfunction, metabolic profile and growth hormone (GH)/insulin-like growth factor (IGF)-I secretion in healthy adult subjects. We investigated the metabolic profile in a cohort of 231 consecutive healthy...
Nivaldo Ribeiro Villela et al.
Journal of translational medicine, 12, 232-232 (2014-08-26)
Relative hypovolemia is frequently found in early stages of severe sepsis and septic shock and prompt and aggressive fluid therapy has become standard of care improving tissue perfusion and patient outcome. This paper investigates the role of the nitric oxide...
C B Christiansen et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 47(7), 537-543 (2015-01-21)
TLQP-21 is a VGF-derived neuropeptide proposed to be involved in regulation of metabolism. More specifically it has been suggested that TLQP-21 has the ability to enhance glucose stimulated insulin secretion, making it a candidate for treatment of patients with type...

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